蒙药山沉香的化学成分和药理活性研究进展

Phytochemical and pharmacological progress on peeled stem of Syringa pinnatifolia,a Mongolian folk medicine

山沉香为蒙药特色药材,局限分布于内蒙与宁夏的贺兰山地区,临床上多用于治疗冠心病心绞痛等心肺疾病。现代研究显示,山沉香主要含木脂素、倍半萜和挥发油类,显示出抗心肌缺血等功效。该文从山沉香的原植物分类、药用资源、化学成分及药理活性等方面对其进行归纳总结,以期为相关的药用资源利用、药效物质阐明及开发应用等奠定基础。

The peeled stem of Syringa pinnatifolia is a Mongolia folk medicine,mainly distributed in Helan mountain,inner Mongolia and Ningxia provinces of China. It has been used for the treatment of cardiopalmus,angina pectoris,and cardiopulmonary diseases for a long history. Contemporary research revealed the presence of major lignans,sesquitepenes,and essential oils,and showed myocardial ischemia related diseases. This review summarizes the plant origins,taxonomic disputes,phytochemical and pharmacological research progress,hopefully to provide reference for full medicinal utilization,clarification of biological effective substance,and drug development.