裸花紫珠黄酮苷类化合物的分离与结构鉴定

Isolation and Structure Identification of Flavonoid Glycosides in Callicarpa nudiflora

目的:研究裸花紫珠95%乙醇提取物的化学成分。方法:采用硅胶,MCI,C_(18)等柱色谱方法对裸花紫珠中化学成分进行分离纯化,并经波谱数据分析和文献对照鉴定化合物结构。结果:从裸花紫珠叶95%乙醇提取物中分离得到8个化合物,分别鉴定为木犀草苷(1),木犀草素-3'-O-β-D-吡喃葡萄糖苷(2),木犀草素-4'-O-β-D-吡喃葡萄糖苷(3),芹菜素-7-O-β-D-葡萄糖醛酸苷丁酯(4),木犀草素-3'-O-(6″-E-咖啡酰)-β-D-吡喃葡萄糖苷(5),木犀草素-4'-O-(6'-E-咖啡酰)-β-D-吡喃葡萄糖苷(6),木犀草素-7-O-(6″-E-咖啡酰)-β-D-吡喃葡萄糖苷(7),木犀草素-7-O-(6″-E-阿魏酰)-β-D-吡喃葡萄糖苷(8)。结论:化合物4为首次从该植物分离得到。

Objective： To study the chemical constituents of 95% ethanol extract of Callicarpa nudiflora. Method： The compounds were separated and purified by silica gel, MCI, and C18 column chromatography,while their structures were identified by analyzing their spectral data and comparing with the previously reported literatures. Result： Eight compounds were isolated from 95% ethanol extract of C. nudiflora and their structures were respectively identified as luteoloside（ 1）,dracocephaloside（ 2）,juncein（ 3）,apigenin-7-O-β-D-glucuronide buthyl ester（ 4）,luteolin-3’-O-（ 6″-E-caffeoyl）-β-D-glucopyranoside（ 5）,luteolin-4’-O-β-D-（ 6″-E-caffeoyl）-glucopyranoside（ 6）,luteolin-7-O-（ 6″-E-caffeoyl）-β-D-glucopyranoside（ 7）,luteolin-7-O-（ 6″-E-feruloyl）-β-D-glucopyranoside（ 8）. Conclusion： Compound 4 was isolated from this plant for the first time.