鳞翅目昆虫昼夜节律的授时机制研究进展

Research progress in the circadian rhythm mechanism of lepidopteron

鳞翅目昆虫生物钟环路的核心成员,在蛋白质分子进化和相互作用网络等方面,与哺乳类,甚至与果蝇等经典模式昆虫有较大差异。总结了昼夜节律对鳞翅目昆虫孵化与进食、生长与变态、生殖与滞育、呼叫与迁徙等生理行为的影响,以及核心钟基因Cry、Per和Tim等的研究进展,分析了鳞翅目昆虫生物钟负反馈环路与哺乳动物和果蝇的差异,介绍了鳞翅目昆虫作为温度授时的生物钟负反馈环路研究和外周生物钟分子机制研究等方面的材料优势。

The zeitgeber plays an important role in the output and input loop of circadian rhythms clock in lepidopteron, which has large differences in the aspects of protein evolution and molecular interaction network with the classic mode insects such as Drosophila melanogaster. In this article, the effects of the circadian clock on hatching, eating, growth, metamorphosis, reproduction, diapause, calling behavior and migration in lepidopteron were summarized, as well as the research progress in core genes of clock signal input circuit in lepidopteron such as Cry, Per and Tim. Then the differences of the biological clock feedback loop between lepidopteron and mammals or Drosophila were compared and analyzed. Through above analysis, we introduced the advantage of lepidopteron as an experimental animal for studying temperature zeitgeber and the peripheral clock mechanism.