参苓白术散联合美沙拉嗪治疗脾胃气虚型溃疡性结肠炎疗效

Effect of Shenling Baizhu powder combined mesalazine treatment of ulcerative colitis of spleen stomach Qi deficiency

目的分析参苓白术散联合美沙拉嗪对脾胃气虚型溃疡性结肠炎的治疗效果。方法选择2011年5月~2014年6月期间我院收治的脾胃气虚型溃疡性结肠炎患者97例,根据随机分组原则分为治疗组和对照组。治疗组采用参苓白术散联合美沙拉嗪进行治疗,对照组仅用美沙拉嗪治疗。比较两组患者治疗有效率、相关评分改善情况以及主要临床症状消失时间。结果 8周治疗后,两组患者临床症状呈现不同程度改善,两组患者治疗有效率、疾病活动指数DAI评分、炎症指标ESR、CRP水平、主要临床症状消失时间比较,治疗组改善效果优于对照组,差异有统计学意义（P〈0.05）。结论参苓白术散联合美沙拉嗪可有效治疗脾胃气虚型溃疡性结肠炎,减轻炎症反应的同时可改善患者体质,缩短疾病治愈时间,具有较高的临床推广价值。

Objective To study and analyze the treatment effect of Shenling Baizhu powder combined mesalazine in the treatment of ulcerative colitis of spleen stomach Qi deficiency. Methods 97 patients with ulcerative colitis of spleen stomach Qi deficiency, who were received and treated in our hospital from May 2011 to June 2014, were selected and were divided into treatment group and control group according to randomized grouping principle. Treatment group was treated with Shenling Baizhu powder combined mesalazine, while control group was only treated with mesalazine. To compare the effective rate of treatment, the improvement condition of correlative evaluation, and the disappearance time of main clinical symptoms between the two groups. Results After 8 weeks treatment, the clinical symptoms of the two groups were improvement at different degree, the effective rate of treatment, the disease active index of DAI score, the inflammatory indexes level of ESR, CRP, the disappearance time of main clinical symptoms compared with the two groups showed that, the improvement effect in treatment group was better than which in control group, the differences was statically significant（P〈0.05）. Conclusion Shenling Baizhu powder combined mesalazine could effectively treat ulcerative colitis of spleen stomach Qi deficiency, could reduce inflammatory response and improve patients＇ constitution, could shorten the healing time of illness, has higher clinical popularization value.