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大麻素系统基因多态性与毒品依赖的研究进展

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摘要 药物依赖是遗传因素、心理因素和社会环境等多因素所致的疾病[1]。脑内伏隔核、纹状体、杏仁核和嗅区等区域是毒品依赖的神经解剖基础,脑内黑质纹状体通路、中脑边缘叶通路和中脑皮质通路等信号通路与毒品依赖病理生理过程密切相关[2]。多巴胺系统参与毒品依赖病理生理过程[1-3]。近年来发现大麻素系统与毒品依赖病理生理过程有关。
出处 《中国药物依赖性杂志》 CAS CSCD 2015年第6期413-416,共4页 Chinese Journal of Drug Dependence
基金 国家自然科学基金(81400966) 四川省教育厅科研基金重点项目(14ZA0191和15ZA0209)资助
关键词 AEA CB1 FAAH 毒品依赖
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