柳州地区HIV阳性产妇所生婴儿出生结局分析

Birth outcomes of infants born to HIV-infected mothers in Liu Zhou

目的了解HIV阳性产妇所生婴儿的出生状况,为开展更科学的HIV阳性孕妇孕产期保健提供理论依据。方法回顾性分析2009-2013年柳州地区所有HIV阳性产妇所生婴儿的出生数据,将其出生体重、出生身长、早产儿发生率、低出生体重发生率及出生缺陷发生率等与WHO标准或柳州地区平均水平进行比较。结果 2009-2013年柳州地区HIV阳性产妇所生婴儿共265例,平均出生体重为(2.83±0.44)kg,平均出生身长为(49.35±2.15)cm。男婴139例,平均出生体重为(2.86±0.40)kg,女婴127例,平均出生体重为(2.79±0.47)kg,HIV阳性产妇所生男婴和女婴的出生体重与WHO标准比较均存在统计学差异(P<0.05)。男、女婴平均出生身长分别为(49.59±1.87)cm、(49.09±2.40)cm,HIV阳性产妇所生男婴与女婴的出生身长与WHO标准比较差异均无统计学意义(P>0.05)。柳州市HIV阳性产妇所生婴儿早产儿发生率为11.70%,低出生体重发生率为16.98%,出生缺陷发生率为22.64‰,均高于柳州地区的整体指标。结论 HIV阳性产妇所生婴儿出生状况不足,加强对HIV阳性孕产妇的孕产期保健工作,将促进HIV阳性产妇所生婴儿的健康出生。

Objective To study the birth status of infants born to HIV-infected mothers and to provide a theoretical basis for the development of infants born to HIV-infected mothers. Methods The birth weight,birth length,incidence of premature,incidence of low birth weight and incidence of birth defects of infants born to HIV-infected mothers in Liuzhou from 2009 to 2013 were analyzed,then comparing with the WHO standards and the overall level of Liuzhou city. Results There were 265 infants born to HIV-infected mothers from 2009 to 2013,the average birth weight of them was（ 2. 83 ± 0. 44） kg and the average birth height was（ 49. 35 ± 2. 15）cm. The average birth weight of 136 males was（ 2. 86 ± 0. 40） kg,and the average birth weight of 127 females was（ 2. 79 ± 0. 47）kg,there were statistical differences compared with WHO standards（ P 〈 0. 05）. The birth height of males and females was（ 49. 59 ±1. 87） cm and（ 49. 09 ± 2. 40） cm,respectively; there were no statistically significant difference compared with WHO standards（ P 〉0. 05）. The incidence of premature of infants born to HIV-infected mothers was 11. 70%,the incidence of low birth weight was16. 98% and the incidence of birth defects was 22. 64‰,which higher than the overall level of Liuzhou city. Conclusions The birth outcomes of the infants born to HIV-infected mothers is not ideal,so it is very necessary to strengthen the maternal health care work for HIV-infected pregnant women to improve the birth outcomes of infants born to HIV-infected mothers.