TACE联合外科手术治疗原发性肝癌的临床观察

Clinical observation of patients with primary liver cancer treated with TACE and surgical operation

目的探讨在原发性肝癌患者中联用肝动脉化疗栓塞（TACE）与外科手术治疗的价值。方法随机将2010年2月-2012年2月我院治疗的50例原发性肝癌患者分组,对照组25例单纯予外科手术治疗,观察组25例选择TACE加外科手术方案治疗,针对两组的临床治疗情况进行评估。结果经相应方案治疗后,观察组的总治愈率、3年存活率相比对照组明显增高,局部复发、远处转移率明显下降,差异有统计学意义（P〈0.05）,术后合并症两组比较相当,差异无统计学意义（P〉0.05）。结论采取TACE与外科手术方案对原发性肝癌患者进行治疗,远近期疗效更理想,治疗更安全,适合加强推广。

Objective To study the value of the patients with primary liver cancer treated with TACE（Transhepatic Arterial Chem Otherapy And Embolization） and surgical operation. Methods From February in 2010 to February in2012,50 cases of patients with primary liver cancer were divided into the treatment group and control group randomly.The control group（25 cases） was given pure surgical operation treatment, and the observation group（25 cases） was given TACE and surgical operation treatment.Then the clinical treatment of the two groups were evaluated. Results After treated with corresponding scheme,the total cure rate and the 3 year survival rate of the observation group were both significantly higher than the control group,but the local recurrence and distant metastasis rate were significantly lower than the control group, with statistical significance（P〈0.05）.The postoperative complications in the two groups was similar, with no statistical significance（P〈0.05）. Conclusion If the patients with primary liver cancer surgery are given TACE and surgical operation treatment, the far and near curative effect are more ideal, safer, and suitable for strengthening promotion.