流动人口肺结核耐药情况及相关因素探讨

Study on Drug Resistance to Tuberculosis and Its Related Factors in Fluid Population

目的 探究流动人口肺结核耐药情况和相关影响因素,并且制定针对流动人口肺结核的防治措施。方法 选取我院2014年2月~2015年2月收治的流动人口中100位肺结核患者作为研究对象,搜集患者的基本情况、病史等信息,然后进行菌型鉴定及利福平、异烟肼、链霉素、乙胺丁醇敏感性测试,通过这些资料数据分析流动人口肺结核耐药性和相关影响因素。结果 100位肺结核患者中部分患者还存在着医疗保障不足的现象,还有一部分患者因为回乡治疗流失。本次研究,患者的总体耐药率是19.25%,初始耐药率是17.02%,获得性耐药率是43.50%。在这几种药物中,链霉素和异烟肼的耐药率是最高的,分别是13.75%、10.84%。通过研究发现,复治患者是流动人口耐药肺结核的相关因素。结论 流动人口肺结核耐药现象比较严重,医院要根据流动人口的肺结核耐药性的特点来进行防治措施。

Objective To study on drug resistance to tuberculosis and its related factors in fluid population in order to carry out prevention measures for tuberculosis. Methods Chose 100 tuberculosis patients in fluid population who were received in hospital from February 2014 to February 2015 as study subjects and made a collection of patients＇ basic information and their disease history at first,then conducted bacteria-type identification and a series of sensitivity test,including rifampicin,isoniazid,streptomycin and ethambutol susceptibility testing, based on tested data to analyze drug resistance to tuberculosis and its related factors in fluid population. Results Of all 100 patients,some of them were still in lack of health care and some of them were out of contact since they were back hometowns for treatment. In this research, patients＇ drug resistance rate was 19.25% in general,while,it was 17.02% originally and acquired drug resistance rate was 43.50%. Among all types of medications,drug resistance rates of streptomycin and isoniazid were the top two highest,which were 13.75% and 10.84% respectively,the research result showed that re-treated patients was the main factor leading to drug resistance to tuberculosis in fluid population. Conclusion Drug resistance to tuberculosis is so prevalent in fluid population,it is required for hospitals to carry out prevention measures in accordance with drug resistance characteristics in fluid population.