175例原发性肝癌中医证型与血清白蛋白相关性的研究

Research on Relationship Between TCM Syndrome Patterns of 175 Primary Liver Cancer Patients and Albumin

目的:探讨175例原发性肝癌患者的中医证型与血清白蛋白的相关性。方法:以2013年3月—2013年12月广西医科大学附属肿瘤医院住院收治原发性肝癌(PLC)初治患者175例为研究对象,将其分为肝气郁结、气滞血瘀、湿热聚毒、肝肾阴虚四组,分析中医证型与患者血清白蛋白(ALB)的相关性。结果:(1)四种证型PLC患者ALB<35 g/L的比率不一致(P<0.05)。(2)肝气郁结型和气滞血瘀型ALB<35 g/L的比率明显低于湿热聚毒和肝肾阴虚型(P多重比较<0.01)。(3)湿热聚毒型ALB<35 g/L的比率明显低于肝肾阴虚型(P多重比较<0.01)。结论:(1)ALB<35 g/L可以作为是中医辨证的客观指标,用于湿热聚毒和肝肾阴虚型鉴别肝气郁结型和气滞血瘀型,也可用于肝肾阴虚型与湿热聚毒型的相互鉴别。(2)PLC患者的ALB水平与中医证型存在一定的相关性。前者对于中医辨证分型有一定的指导意义。

Objective：To investigate the relationship between TCM syndrome patterns and albumin （ALB） from the informa- tion of 175 primary liver cancer （PLC） patients. Methods ： 175 PLC patients in initial treatment who hospitalized in Affiliated Tumor Hospital of Guangxi Medical University from March to December in 2013 were divided into four groups such as depression of liver - Qi, stagnation of vital energy and blood stasis, heat - damp and poly poison and liver - kideny Yin deficiency. To analyze the relationship between PLC patients＇ TCM syndrome patterns and ALB. Results ： （ 1 ） Four TCM syndrome patterns of PLC pa- tients were not coincident in the rate of ALB 〈 35 g/L（P 〈 0.05 ）. （2） The rate of ALB 〈 35 g/L in depression of liver - Qi and stagnation of vital energy and blood stasis was obvious lower than that of heat - damp and poly poison and liver - kideny Yin defi- ciency（ Pmultiple comparison 〈 0.01 ）. （3）The rate of ALB 〈 35 g/L in heatidamp and poly poison was obvious lower than liver - kideny Yin deficiency（ Pmultiple comparison 〈 0.01 ）. Conclusion ： （ 1 ） ALB 〈 35 g/L can be considered as objective reference to confirm TCM syndrome patterns of PLC patients. It can be used in discrimination between heat -damp and poly poison,liver- kideny Yin deficiency and depression of liver - QIi, stagnation of vital energy and blood stasis. It also can be used in discrimina- tion between heat - damp and poly poison and liver - kideny Yin deficiency. （2） There are some relationships between ALB and TCM syndrome patterns of PLC patients. And the former has the value of guidance to confirm the latter.