摘要
目的研究酒精依赖对个体脑电信号的影响,以期了解酒精依赖对个体健康的影响。方法基于亨利(纽约州立大学)实验所得的102例脑电数据,对数据进行预处理,去除伪迹,提取脑电特征波并计算包含功率谱、R值和重心频率在内的脑电参数,进行统计学分析,以讨论分析酒精依赖患者与健康人的脑电差异。结果相对于健康人,酒精依赖患者的脑电中α波相对功率减小,其中以顶区和枕区最为显著。θ波功率减小,在颞叶的变化较为明显。β波相对功率在各个脑区均大幅提高。全脑区R值均减小,重心频率均增大。结论相对于健康人群,酒精依赖患者的脑电信号普遍向高频迁移,表明酒精依赖可以使大脑皮质的兴奋度增强,脑活动更为复杂。
Objective Aiming at studying the influences of alcohol dependence on individual brain electric signals,we made a comparison between the patients with alcohol dependence and the healthy control subjects,expecting to get the impact of alcohol on individuals. Methods One hundred and two cases of EEG data used in this paper were from Henry＇ s experiment in State University of New York. After removing the artifact, extracting the EEG feature waves and calculating the relevant EEG parameters, the statistics analysis was done to analyze the difference of EEG between alcoholics and healthy control subjects. Results Compared with healthy control subjects, the alcoholics＇ relative power of ct band decreased, especially in parietal and occipital regions. The power of 13 band decreased,especially in temporal region. The power of 13 band increased in all brain regions. The R-value decreased while the gravity frequency increased in each region. Conclusions Alcohol dependence makes patients＇ EEG signals migrates to the high frequency,increases the excitability of cerebral cortex and makes brain activities more complicated.
出处
《北京生物医学工程》
2015年第6期568-572,共5页
Beijing Biomedical Engineering
基金
"十二五"国家科技支撑计划(2012BAI23B07)
国家自然科学基金(61171059
61075107)
中央高校基本科研业务费专项资金(NZ2013307)资助
关键词
脑电信号
酒精依赖
重心频率
尺值
electroencephalography signal
alcohol dependence
gravity frequency
R-value
