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基于fNIRS的脑功能连接研究综述 被引量：6

Review of functional brain connectivity based on fNIRS
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摘要 脑功能连接是指脑皮质区域间在神经生理活动上的相互关联,在大脑功能分析中具有重要的地位和作用。功能性近红外光谱技术(functional near-infrared spectroscopy,fNIRS)作为一种新兴的神经影像学工具在脑功能连接的研究领域中愈加受到重视。本文首先简要介绍了fNIRS应用于脑功能检测的基本原理,并结合f MRI从多角度分析了fNIRS应用在静息态脑功能连接研究中的优势与可行性,然后重点介绍了脑功能连接的两种主要分析方法——种子相关分析和基于图论的静息态复杂脑网络分析,最后讨论了基于fNIRS的脑功能连接在认知障碍及相关疾病研究中的应用,使读者对基于fNIRS的脑功能连接的基本理论、研究方法及发展现状有一个较为清晰全面的了解。 during the neural Functional brain connectivity refers to the associations between different cortical areas physiological activity, which plays an important role in the analysis of brain function. Functional near infrared spectroscopy （fNIRS）has been paid more and more attention in the field of functional brain connectivity. In this paper, we first briefly introduce the basic principle of fNIRS, and summarize the advantage and feasibility of fNIRS to assess resting-state functional connectivity in comparison with fMRI. Then two typical methods of analysis of functional brain connectivity based on fNIRS are reviewed, namely seed-based correlation analysis and resting-state complex brain network analysis based on graph- theoretical. Finally,a discussion on the application of functional brain connectivity for the studies of cognitive dysfunction and related mental illness is provided. Readers can have a clear and comprehensive understanding of the basic theory,research methods and development status of functional brain connectivity based on fNIRS.
作者 赵佳
机构地区 北京交通大学计算机与信息技术学院
出处 《北京生物医学工程》 2015年第6期633-638,656,共7页 Beijing Biomedical Engineering
基金 中央高校基本科研业务费专项资金(2013JBZ014)资助
关键词 功能性近红外光谱技术 功能连接 复杂脑网络 图论 小世界特性 functional near-infrared spectroscopy functional connectivity complex networks graphtheory small-world characteristics
分类号 R318.04 [医药卫生—生物医学工程]
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参考文献35

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二级参考文献51

  • 1杨炯炯,曾绍群,骆清铭,管林初,匡培梓,龚辉,Britton Chance.左前额叶参与非相关词对的语义编码过程──来自光学成像的佐证[J].心理学报,2001,33(1):48-54. 被引量：11
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共引文献43

同被引文献76

引证文献6

二级引证文献34

北京生物医学工程
2015年 第6期

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