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NSE和MMP-9检测在脑膜炎中的诊断价值 被引量:8

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摘要 目的评价神经元特异性烯醇酶(NSE)和基质金属蛋白酶(MMP-9)对化脓性脑膜炎和病毒性脑膜炎的诊断价值。方法分别采用双抗体夹心、化学发光法测定检测60例脑膜炎患者和25例健康对照者脑脊液及血清内MMP-9及NSE水平。结果化脑组病脑组分别与对照组比较,化脑组与病脑组比较,,差异有统计学意义(P<0.05)。结论 MMP-9、NSE参与了中枢神经系统感染脑功能损伤的病理生理过程,监测脑脊液中MMP-9、NSE的水平可作为化脓性脑膜炎和病毒性脑炎早期辅助诊断、鉴别诊断指标。
作者 周亚玲
出处 《国际检验医学杂志》 CAS 2015年第24期3619-3621,共3页 International Journal of Laboratory Medicine
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