肥胖对结直肠癌手术部位感染的影响

Impact of obesity on surgical site infection following colorectal cancer surgery

目的探讨肥胖对结直肠癌手术部位感染(SSI)的影响。方法回顾性调查2008年1月—2013年12月某院行结直肠癌根治性手术的215例患者,其中100例体重指数(BMI)≥25 kg/m2(肥胖组),115例BMI<25 kg/m2(正常体重组),比较两组患者术中情况、术后恢复、手术并发症等指标。结果肥胖患者72例(72.00%)术中出血量>60 mL,58例(58.00%)手术持续时间>220 min,其中20例(20.00%)发生SSI;正常体重组中仅30例(26.09%)术中出血量>60 mL,20例(17.39%)手术持续时间>220 min,8例(6.96%)发生SSI。肥胖组患者术中出血量、SSI发病率高于正常体重组,手术持续时间、术后住院时间长于正常体重组,各组比较,差异均有统计学意义(均P<0.05)。结论结直肠癌患者SSI发病率较高,肥胖、手术持续时间长、出血量多是结直肠患者SSI的危险因素。

Objective To evaluated the impact of obesity on surgical site infection（SSI）following colorectal cancer surgery.Methods A total of 215 patients undergoing radical surgery for colorectal cancer in a hospital between January 2008 and December 2013 were investigated retrospectively,100 patients were with body mass index（BMI）≥25 kg/m2（obesity group）and115 patients with BMI25 kg/m2（normal weight group）,the intra-operative and postoperative indicators and surgical complications were compared between two groups.Results In obesity group,72（72.00%）patients had intra-operative blood loss of60 mL,58（58.00%）patients＇ duration of surgery was220 min,20（20.00%）of whom developed postoperative SSI;in normal weight group,30（26.09%）patients had intra-operative blood loss of60 mL,20（17.39%）patients＇ duration of surgery was220 min,8（6.96%）of whom developed postoperative SSI.Intra-operative blood loss and incidence of SSI in obesity group were both significantly higher than normal weight group,duration of surgery and postoperative length of hospital stay were both longer than normal weight group（both P0.05）.Conclusion Incidence of SSI in colorectal cancer patients is high.Obesity,long duration of surgery,and more bleeding are high risk factors for SSI in colorectal cancer patients.