血栓通注射液联合奥曲肽治疗急性胰腺炎疗效的系统评价

Efficacy of Xueshuantong injection combined with octreotide in the treatment of acute pancreatitis

目的评价血栓通注射液联合奥曲肽治疗急性胰腺炎的疗效。方法检索CNKI数字图书馆、万方数据库、维普数据库、Pubmed、Cochrane Library、Embase和SCI等数据库中血栓通注射液联合奥曲肽治疗急性胰腺炎的随机对照试验(RCT)。采用Rev Man5.1软件对入选试验进行Meta分析。结果共有7项RCT包括410例病例被纳入本研究,Meta分析结果显示,试验组总有效率显著高于对照组(P<0.01),试验组住院时间较对照组短,差异具有统计学意义(P<0.01)。结论血栓通注射液联合奥曲肽治疗急性胰腺炎较单用奥曲肽总有效率高,且可以减少住院时间。

Objective To evaluate the treatment effects of acute pancreatitis using Xueshuantong and octreotide. Methods The randomized controlled trials data regarding the acute pancreatitis treatment with Xueshuantong and octreotide were retrieved from the database including China National Knowledge Infrastructure, Wan Fang database, VIP database, Pub Med, Cochrane Library, Embase and SCI. Those experiment results were analyzed by Rev Man5.1. Results Seven randomized controlled trials and 410 patients were brought into this study. The significant difference in the treatment effective rate（P〈0.01） and in the reducing in-hospital day（P〈0.01） were observed between control and experimental group. Conclusion Xueshuantong plus octreotide can improve the total effective rate of acute pancreatitis treatment, and reduce in-hospital day.