桂皮醛药理作用的研究进展

Research progress of trans-cinnamaldehyde pharmacological effects

桂皮醛是中国传统中药材桂枝或肉桂挥发油的主要成分,为烯醛类有机化合物,具有抗炎、解热镇痛、抗肿瘤、抗菌、降糖、抗肥胖和神经保护等多种药理作用。对神经系统、心血管、肿瘤、糖尿病等疾病均有一定的防治作用,作为预防保健的天然药物具有较好临床和市场潜力。该文对近5年来国内外关于桂皮醛的药理作用及其机制研究进行了综述,以期对桂皮醛的深入研究和开发提供一定的科学依据。

Trans-cinnamaldehyde,the main component of volatile oil from cassia twig or Cinnamomum cassia,which is a traditional Chinese herbal medicine. Trans-cinnamaldehyde is a kind olefine aldehyde of organic compounds and has many pharmacological properties,such as anti-inflammatory,anti-tumor,anti-bacterial,antidiabetic,anti-obesity,and neuroprotection etc. The compound has preventive and therapeutic effects on the nervous system,cardiovascular,cancer,diabetes and other diseases. Trans-cinnamaldehyde,as a preventive care of nature medicine,has great clinical and market potential. This paper gives a review about the pharmacological effects and mechanism of trans-cinnamaldehyde researched in the latest five years. We hope to provide some basic information for further research on trans-cinnamaldehyde.