蒽环类药物致心脏不良反应监测的研究进展
被引量:2
摘要
蒽环类药物(Anthracyline,ANT)在临床抗癌药物中,占有举足轻重的地位,尤其对实体肿瘤和造血系统方面,并呈现着明显的剂量-效应线性关系。然而,随着剂量的增加,脱发、骨髓抑制、心脏毒性等不良反应也成比例增加,尤其在心脏毒性方面,尤为突出,这严重限制了其在临床中的长期使用。现就国内外近年蒽环类心脏毒性的监测等方面的进展进行总结,为蒽环类心脏毒性的深入研究提供参考。1
出处
《包头医学院学报》
CAS
2015年第12期143-145,共3页
Journal of Baotou Medical College
参考文献15
-
1Octavia Y, Tocchetti CG, Cabrielson KL, et al. Doxorubicin - induced cardiomyopathy: from molecular mecha - nisms to therapeutic strategies [ J ]. J Mol Cellular Cardiol, 2012,52 (6) : 1213 - 1225.
-
2RVitelli M, Filippelli A, Rinaldi B, et al. Effects of doco - sahexaenoic acid on [ Ca2 + ] increase induced by doxoru - bicin in ventricular rat cardiomyocytes [ J ]. Life Sci,2002,71 (16) :1905 -1916.
-
3Carvalho FS, Burgeiro A, Garcia R, et al. Doxorubicin - in- duced cardiotoxicity:from bioenergetic failure and cell death to cardiomyopathy[ J]. Med Res Rev, 2014,34 ( 1 ) : 106 - 135.
-
4Trachtenberg BH, Landy DC, Franco VI, et al. Anthracy- cline - associated eardiotoxieity in survivors of childhood cancer[ J ] Pediatr Cardio1,2011,32 ( 3 ) :342 - 353.
-
5Seully RE, Lipshultz SE. Anthracycline cardiotoxicity in long -term survivors of childhood cancer [ J 1. Cardiovasc Toxi- col.2007.19( 1 ) : 122 - 128.
-
6冯品宁,刘敏,崔颖鹏,叶曼曼,张式鸿,姜傥.心肌肌钙蛋白T、肌钙蛋白I及CK-MB诊断急性心肌梗死临床应用价值的比较分析[J].中国实验诊断学,2008,12(10):1256-1258. 被引量:60
-
7Horacek JM, Pudil R, Jebavy I, et al. Assessment of anthra- cycline - induced cardiotoxicity with biochemical markers [ J ]. Exp Oncol, 2007, 29 (4) : 309 - 313.
-
8Mladosievicova B, Urbanova D, Radvanska E, et al. Role of NT - proBNP in detection of myocardial damage in childhood leukemia survivors treated with and without anthracyelines [ J]. Exp Clin Cancer Res,2012,31:86.
-
9Horaeek JM, VasatovaM, TiehyM, et al. The use of cardiac bio - markers in detection of cardiotoxicity associated with conventional and high - dose chemotherapy for acute leuke- mia [J]. Exp Oncol,2010, 32(2): 97 -99.
-
10Khositseth A, Jirasakpisarn S, Pakakasama S, et al. Carniti- nelevels and cardiac functions in children with solid malig- nancies receiving doxorubicintherapy [ J]. Indian J Med Pae- diatr Oncol,2011 ;32( 1 ) :38 -42.
二级参考文献18
-
1王咏梅,殷仁富,吴宗贵,梅长林,顾书华.左旋肉碱治疗急性病毒性心肌炎的临床疗效分析[J].中国综合临床,2004,20(6):488-489. 被引量:14
-
2敬华,李丹,王晓非,陈兴明,高铁山,杨晋德,魏萍.几种心肌损伤标志物对急性心肌梗死的诊断效率[J].中国实验诊断学,2006,10(3):258-261. 被引量:27
-
3Bryant J, Picot JL, Baxter L. Use of cardiac markers to assess the toxic effects of anthracyclines given to children with cancer: a systematic review [J]. Eur J Cancer,2007, 43(13) : 1959-1966.
-
4Tokarska-Schlattner M, Zaugg M, Zuppinger C, et al. New insights into doxorubicin-induced cardiotoxicity: the critical role of cellular energetics [J].J Mol Cell Cardiol, 2006, 41 (3) : 389-405.
-
5Yoon HR, Hong YM, Boriack RL, et al. Effect of L-carnitine supplementation on cardiac carnitine palmitoyhransferase activities and plasma carnitine concentrations in adriamycin-treated rats [J]. Pediatric Res,2003,53 (5): 788-792.
-
6Bryant J, Picot J, Levitt G, et al. Cardioprotection against the toxic effects of anthracyclines given to children with cancer: a systematic review [J]. Health Technol Assess, 2007,11 (27) : 1-84.
-
7Iarussi D, Indolfi P, Casale F, et al. Anthracycline- induced cardiotoxicity in children with cancer: strategies for prevention and management [J ]. Pediatr Drugs,2005, 7 (2) :67-76.
-
8Delaney CE, Hopkins SP, Addison CL. Supplementation with L-caruitine does not reduce the efficacy of epirubicin treatment in breast cancer cells [J]. Cancer Lett,2007, 252(2) : 195-207.
-
9Wu AHB, Apple FS, Gibler, WB, et al. National Academy of Clinical Biochemistry standards of laboratory practice: recommendations for the use of cardiac markers in coronary arter diseases[J]. Clin Chem, 1999,45: 1104.
-
10The joint European Society of cardiology/American college of cardiology Committee. Myocardial infarction redefined-A consensus document of the Joint European Society of cardiology/American college of cardiology Committee for the redefinition of myocardial infarction[S]. J Am Coll Cardial, 2000, 36: 959.
共引文献63
-
1李建,李海燕.生化与心功能指标与AMI的相关性[J].临床心电学杂志,2020(2):112-116.
-
2苗微微,程晓玲.高敏肌钙蛋白T与心肌梗死三联诊断急性心肌梗死价值分析[J].中国老年学杂志,2014,34(1):233-234. 被引量:8
-
3邱海山,刘仿,何继宏,严慧芳,钟羡,林保安.肌钙蛋白T在诊断急性心肌梗死中的应用价值[J].医学信息(中旬刊),2010,5(8):2287-2289.
-
4徐欣怡,黄美蓉.蒽环类抗肿瘤药物的心脏毒性[J].临床儿科杂志,2010,28(7):694-696. 被引量:6
-
5胡振奎,吴伟敏,姜敏炎,王强,黄俊,王永仿,巢齐放.曲美他嗪预处理对瓣膜置换患者的心肌保护作用[J].江苏大学学报(医学版),2010,20(4):335-338. 被引量:2
-
6贝宁.比较分析TNT和TNI的测定对急性心肌梗死的诊断价值[J].健康天地(学术版),2010,4(8):20-21. 被引量:3
-
7阳维德,黄立伟.非心源性心肌酶显著增高的临床特点分析[J].中国实验诊断学,2010,14(9):1458-1459. 被引量:4
-
8任占宝,王金英,李晓阳,宋建梅.三种方法测定肌钙蛋白Ⅰ分析性能的比较与评价[J].标记免疫分析与临床,2010,17(5):321-323. 被引量:4
-
9苏月南,关常青,梁健.检验危急值在内科急症患者的合理应用[J].国际检验医学杂志,2010,31(11):1317-1318. 被引量:5
-
10沈婵,饶艳,王焱林,张宗泽,王成夭,李卉,王赘.乳化异氟醚预处理对大鼠心肌缺血再灌注时NF—kB活性的影响[J].中华麻醉学杂志,2010,30(12):1469-1471. 被引量:3
同被引文献24
-
1Nielsen TO O,M-B,Gao D,Leung S,et al.High risk premenopausal luminal A breast cancer patients derive no benefit from adjuvant chemotherapy:Results from DBCG77B randomized trial[C].Presented at the 2015 San Antonio Breast Cancer Symposium;San Antonio,Texas,December 8-12,2015.Abstract Sl-08.
-
2Sparano JA,Gray RJ,Makower DF,et al.Prospective validation of a 21-Gene expression assay in breast cancer[J].N Engl J Med,2015,373(21):2005-2014.
-
3Chavez--MacGregor M,Clarke CA,Lichtensztajn DY,et al.Delayed initiation of adjuvant chemotherapy among patients with breast cancer[J].JAMA Oncol,2015,Dec 10:1-8.doi:10.1001/jamaoncol.2015.3856.[Epub ahead of print].
-
4Gagliato DDM,Gonzalez-Angulo AM,Lei X,et al.Clinical Impact of delaying initiation of adjuvant chemotherapy in patients with breast cancer[J].J Clin Oncol,2014,32(8):735-744.
-
5Sparano JA,Zhao F,Martino S,et al.Long-term follow-up of the El 199 phase III trial evaluating the role of taxane and schedule in operable breast cancer[J].J Clin Oncol,2015,33(21):2353-2360.
-
6Del ML,De Placido S,Bruzzi P,et al.Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer:an open-label,2 x 2 factorial,randomised phase 3 trial[J].Lancet,2015,385(9980):1863-1872.
-
7Citron ML,Berry DA,Cirrincione C,et al.Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer;first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741[J].J Clin Oncol,2003,21(8):1431-1439.
-
8Samuel JA,Wilson JW,Bandos H,et al.NSABP B-36:A randomized phase III trial comparing six cycles of 5- fluorouracil(5-FU),epirubicin,and cyclophosphamide(FEC)to four cycles of adriamycin and cyclophosphamide(AC)in patients(pts)with node-negative breast cancer[C].Cancer Res,2015,75(9S).Abstract nr S3-02.
-
9Slamon D,Eiermann W,Robert N,et al.Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel(AC->T)with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab(AC->TH)with docetaxel,carboplatin and trastuzumab(TCH)in Her2neu positive early breast cancer patients:BCIRG 006 Study[C].Cancer Res,2009,693(24):500S.
-
10Slamon D,Eiermann W,Robert N,et al.Adjuvant Trastuzumab in HER2-Positive Breast Cancer[J].New Engl J Med,2011,365(14):1273-1283.
二级引证文献8
-
1廖亚勇,马蕊,姚金娥.化疗联合深部热疗对乳腺癌协同抗肿瘤效应分析[J].上海医药,2017,38(9):30-32. 被引量:2
-
2邹易恒,李威,吴越,孟祥实,王兴强,曹梅,孙美超.蒽对脊尾白虾存活、免疫和能量分配的影响[J].河北渔业,2020,0(3):13-17. 被引量:1
-
3王思源,王晓聪,陈盛阳,王武龙,吕金燕,高文斌.参芪扶正注射液防治老年患者蒽环类药物心脏毒性的多中心前瞻性临床研究[J].内蒙古民族大学学报(自然科学版),2020,35(4):336-339. 被引量:3
-
4马建敏,陈雪英,陈晓菲,孙品,何香芹,姜志荣.二维斑点追踪纵向应变评价蒽环类药物对乳癌病人左心房功能影响[J].青岛大学学报(医学版),2020,56(6):671-674.
-
5孙一琦,李新刚,沈素.以多柔比星为基础的化学药物治疗致心脏毒性相关危险因素研究进展[J].中南药学,2021,19(3):500-506. 被引量:2
-
6郭松霖,乔元勋,于淼,薛一涛.中医药防治化疗药物心脏毒性研究进展[J].中医学报,2021,36(8):1668-1673. 被引量:11
-
7马腾,朱明军,王永霞,李彬,郑超楠,贾梦楠,于丽,常鑫迪.参麦注射液联合右丙亚胺防治蒽环类药物心脏毒性的Meta分析及GRADE评价[J].中医杂志,2021,62(18):1598-1605. 被引量:8
-
8张梦棣,浦冬青,时光喜,李静蔚.中药注射液防治化疗相关心脏毒性的系统评价再评价[J].中国医药导报,2023,20(29):144-151.
-
1杨光,仲来福.镉所致肾毒性及氧化性损害机制[J].毒理学杂志,2005,19(A03):233-233. 被引量:3
-
2覃业语,苏素文.抗肿瘤药物心脏毒性作用机制研究进展[J].海南医学,2015,26(24):3661-3664. 被引量:11
-
3费洪文,王新房,谢明星,何亚乐.组织多普勒超声评价阿霉素诱导兔心肌病早期松弛功能改变的实验研究(英文)[J].中国临床药理学与治疗学,2005,10(7):738-742.
-
4谢蒂立,钟萍,王文艳,金静.磷酸肌酸治疗老年舒张性心力衰竭的疗效评价[J].实用医院临床杂志,2011,8(3):32-33. 被引量:4
-
5王永强,严宏.谷氨酸对视网膜缺血的损害机制和相关治疗策略[J].国际眼科杂志,2005,5(5):1006-1009. 被引量:5
-
6周岩芬,马小川.EF值〉50%心衰的无创诊断评估[J].实用心脑肺血管病杂志,2016,24(B04):102-103.
-
7谢伟,黄巨恩.顺铂肾损害的基础研究[J].蛇志,2008,20(2):146-148. 被引量:3
-
8戴冽.非甾体抗炎药的胃肠损害及其防治[J].中国药物与临床,2002,2(1):33-35. 被引量:5
-
9王玉秀,范传玲.阿司匹林对胃肠道黏膜损伤的原因分析及预防用药监护[J].护理研究(下旬版),2006,20(1):196-198. 被引量:6
-
10刘艳,马明月,张玉敏,李海山,崔金山,王旭薇.乙醇对雄性生殖内分泌系统的损害及其机制[J].中国工业医学杂志,2000,13(4):206-209. 被引量:8