苦杏仁煎煮工艺研究

Study on Boiling Process of semen Armeniacae Amarum

目的：优选苦杏仁最佳煎煮工艺。方法：采用HPLC法,以苦杏仁苷煎出率为考察指标,对冷水投药和沸水投药两种投药方式进行考察,比较两种投药方式的优劣;在筛选出最佳投药方式后,采用L9（3^4）正交试验,以干膏率和苦杏仁苷煎出率为考察指标,对苦杏仁煎煮工艺进行优选。结果：苦杏仁的最佳煎煮方法为捣碎成粗粉,取12倍水煮沸后投药,煎煮3次,每次20min。结论：将苦杏仁捣碎成粗粉后沸水投药进行煎煮,有利于保证苦杏仁的临床用药安全和疗效。

Objective：To optimize the best boiling method of semen Armeniacae Amarum.Methods：HPLC method was used to examine indicators of amygdalin fried rate.To inspect the dosing ways in cold water and boiling water,and compare the above two ways;After screening the best dosage,L9（3^4）orthogonal experiment method was used to examine the indicators of dry extract rate and amygdalin fried rate,to optimize the best boiling process of the bitter almond.Results：The best decoction way of the bitter almond was boiling water dosing,8times of water,boiling 2times,each time 20 min.Conclusion：In order to ensure the clinical safety and efficacy of semen Armeniacae Amarum processed products,that should be broken up into coarse powder and dosing in boiling water to boil.