浅谈甲状腺功能亢进症患者血清抵抗素水平与血糖、血脂及甲状腺激素的关系

Relationship Between Serum Resistin Levels and Blood Glucose,Blood Lipid and Thyroid Hormone in Patients with Hyperthyroidism

目的对甲状腺功能亢进症患者的血清抵抗素水平与血糖、血脂及甲状腺激素的关系进行分析和探讨。方法选择2013年4月至2014年5月我院收治的60例甲状腺功能亢进患者作为本次研究的实验组,另选择60例健康人员作为本次的对照组。结果实验组患者的空腹血糖高于对照组,T-CH、LDL-C低于对照组(P<0.05);实验组患者的FT3、FT4、胰岛素、抵抗素、HOMA-IR明显高于对照组、TSH明显低于对照组(P<0.05);甲状腺功能亢进症患者的血清抵抗素水平与FT3、FT4、HOMA-IR呈正相关关系,与T-CH、LDL-C呈负相关关系。结论甲状腺功能亢进症患者血清抵抗素水平与血糖、血脂及甲状腺激素有密切的关系。

Objective To explore the relationship between serum resistin levels and blood glucose, blood lipids and thyroid hormone in patients with hyperthyroidism. Methods The serum resistin levels and blood glucose, blood lipids and thyroid hormone in 60 patients with hyperthyroidism and 60 healthy controls were detected. Results The fasting blood glucose concentration in patients with hyperthyroidism was higher than that of controls, but the T- CH and LDL- C levels were less than that of control group （ P 〈 0.05 ）. The FT3, FT4, insulin, resistin and HOMA-IR in patients were significantly higher than those in the control group, and TSH was significantly lower than that of the control group （P 〈 0.05 ）. The serum resistin levels in patients with hyperthyroidism was positively related with the levels of FT3, FT4 and HOMA-IR, and negatively related with T-CH and LDL-C levels. Conclusion The serum resistin levels in patients with hyperthyroidism are closely related with thyroid hormone, blood lipid and blood glucose.