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联合瑞格列奈及地特胰岛素治疗老年2型糖尿病疗效观察

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摘要 目的探讨老年2型糖尿病治疗中地特胰岛素联合瑞格列奈治疗效果。方法选取2014年6月至2015年6月间于我院住院治疗的老年2型糖尿病患者共64例,将其以随机分组的形式均分为试验组及对照组,每组32例。对照组患者行中性低精蛋白锌胰岛素联合瑞格列奈治疗,试验组患者行瑞格列奈联合地特胰岛素进行治疗,观察对比两组患者治疗效果及各项相关指标改变情况。结果治疗后两组患者FPG,Hb A1C及2h PG水平均存在明显改善(P<0.05),但组间对比无明显差异(P>0.05);治疗期间试验组仅1例患者出现低血糖情况,对照组患者6例出现低血糖情况,两组对比,差异存在统计学意义(P<0.05);治疗后试验组患者平均体重增加0.64kg,对照组患者平均体重增加1.72kg,试验组明显优于对照组,但差异无统计学意义(P>0.05)。结论联合瑞格列奈及地特胰岛素治疗老年2型糖尿病效果显著,且副作用较小,值得进一步推广使用。
出处 《中国老年保健医学》 2015年第6期49-50,共2页 Chinese Journal of Geriatric Care
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