骨密度和25羟维生素D在骨质疏松性髋部骨折的作用

The effect of bone mineral density and 25OHD on the osteoporotic hip fracture

目的在股骨颈骨密度达到骨质疏松阈值的情况下,比较髋部骨折与无髋部骨折患者的年龄、骨密度和25羟维生素D,了解这些因素对髋部骨折的影响。方法对137例骨密度达到骨质疏松阈值的绝经后女性患者进行研究,无髋部骨折组62例,髋部骨折组75例,检测股骨颈骨密度和血清25羟维生素D,比较二组年龄、股骨颈骨密度和25羟维生素D水平。结果无髋部骨折组:年龄:(67.92±8.52)岁,股骨颈骨密度:(0.5064±0.0706)g/cm2,T值:-3.10±0.60,25OHD:(24.90±8.98)ng/ml。髋部骨折组:年龄:(78.49±8.52)岁,股骨颈骨密度:(0.4506±0.0983)g/cm2,T值:-3.51±1.18,25OHD:(14.89±8.94)ng/ml。结论在股骨颈骨密度达到骨质疏松阈值的情况下,髋部骨折患者具有更高年龄,更低骨密度和25羟维生素D。

Objective To compareage,bonemineral density,and 25 OHD between theosteoporotic patients with and without hip fractures for understanding influenceof thesefactors in thehip fracture. Methods Therewere137 postmenopausal women with BMD under- 2. 5 SD in thefemoral neck in our series,including 62 patients without hip fractureand 75 patients with hip fracture.BMD measurement of femoral neck and serum 25 OHD wereexamined. Age,BMD,and 25 OHD werecompared between thepatients with and without hip fractures. Results Theage,BMD of thefemoral neck,T score,and 25 OHD were67. 92 ± 8. 52 yrs,0. 5064 ± 0. 0706 g / cm2,- 3. 10 ± 0. 60,and 24. 90 ± 8. 98 ng /ml,respectively,in theosteoporotic patients without hip fracture. They were78. 49 ± 8. 52 yrs,0. 4506 ± 0. 0983 g / cm2,- 3. 51 ± 1. 18,and 14. 89 ± 8. 94 ng /ml,respectively,in theosteoporotic patients with hip fracture. Conclusion Under thecondition of T≤- 2. 5 SD of femoral neck BMD,thepatients with hip fractureareolder,lower in femoral neck BMD and 25 OHD than thepatients without hip fracture.