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宫颈癌盆腔淋巴结转移的危险因素分析 被引量:1

Risk Factors of cervical cancer with pelvic lylmph node metastasis
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摘要 目的探讨宫颈癌盆腔淋巴结转移的相关危险因素。方法对502例Ⅰb-Ⅱb期宫颈癌根治术后患者的临床与病理资料进行回顾性分析。结果盆腔琳巴结转移率为21.91%(110/502),单因素分析显示肿瘤大小、临床分期、肌层浸润深度、宫旁切缘、病理分级、脉管瘤栓与盆腔淋巴结转移有关(P<0.05)。Logistic回归多因素分析显示肌层浸润深度、临床分期、病理分级、脉管瘤栓为盆腔淋巴结转移的独立危险因素(P<0.05)。结论临床分期晚,病理分级差,肌层浸润>1/2,脉管瘤栓阳性为宫颈癌淋巴结转移的高危因素。 Objective To investigate the risk factors of cervical cancer with pelvic lylmph node metastasis. Methods The clinical and pathological data of 502 patients with cervical carcinoma of stage Ⅰ b -Ⅱ b after radical hysterectomy and pelvic lymphadenectomy were ret- rospectively analysed. Results The rate of lymphnode metastasis was 21.91%. In univariate analysis, pelvic lymph node metastasis was asso- ciated with tumor size, clinical stage, myometrial invasion, parametrial extension, pathological grade and lymph vascular space involvement ( P 〈 0. 05 ). While in Logistic multivariate analysis, the independent factors included pathological grade, clinical stage, pathological grade and lymph vascular space involvement( P 〈 0. 05 ). Conclusion The late stage, worse in pathological grade, myometrial invasion 〉 1/2, positive lymph vascular space involvement are the high risk factors of lymph node metastasis.
作者 吕琳
出处 《河南外科学杂志》 2015年第6期7-8,共2页 Henan Journal of Surgery
关键词 宫颈癌 淋巴结转移 高危因素 Cervical cancer Lymph node metastasis Risk factors
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参考文献6

  • 1余慧敏,易村犍.子宫颈癌ⅠB~ⅡB期盆腔淋巴结转移危险因素分析[J].中国妇幼保健,2011,26(20):3070-3072. 被引量:5
  • 2Zheng M,Huang L,Liu J,et al.Type II radical hysterectomy and adjuvant therapy for pelvic lymph node metastasis with stage IB–IIB cervical carcinoma:A retrospective study[J].J Surg Oncol,2011,1-5.
  • 3Ying Li,Wen-Jie Zeng,Feng Ye,et al,Application of h TERC in thinprep samples with mild cytologic abnormality and HRHPV positive[J],Gynecol Oncol,2011,120(1):73-83.
  • 4Macdonald OK,Chen J,Dodson M,et al.Prognostic significance of histology and positive lymph node involvement following radical hysterectomy in carcinoma of the cervix[J].Am J Clin Oncol,2009,32(4):411-416.
  • 5Pieterse QD,Kenter GG,Gaarenstroom KN,et al.The number of pelviclymph nodes in the quality control and prognosis of radical hysterectomy for the treatment of cervical cancer[J].Eur J Surg Oncol,2007,33(2):216.
  • 6Philippe Morice,Damienne Castaigne,Patricia Pautier,et al.Interest of pelvic and paraaortic lymphadenectomy in patients with stage IB and IIcervical carcinoma[J].Gynecologic Oncology,1999,73(1):106.

二级参考文献12

  • 1温宏武,孙晓梅,刘喆,廖秦平.子宫颈癌盆腔淋巴结转移规律及其临床意义[J].中国实用妇科与产科杂志,2007,23(4):281-283. 被引量:11
  • 2Noriaki Sakuragi, Chikara Satoh, Naoki Takeda. Incidence and distribu- tion pattern of pelvic and paraaortic lymph node metastasis in patients with stages IB, IIA, and IIB cervical carcinoma treated with radical hys- terectomy [J]. Cancer, 1999, 85 (7): 1547.
  • 3Shing - Shun, Nelson Siu, Tak - Hong Cheung, et al. Is common iliac lymph node dissection necessary in early stage cervical carcinoma[J]. Gynecologic Oncology, 2006, 103 (1) : 58.
  • 4Pieterse QD, Kenter GG, Gaarenstroom KN, et al. The number of pelvic lymph nodes in the quality control and prognosis of radical hysterectomy for the treatment of cervical cancer [J]. Eur J Surg Oncol, 2007, 33 (2) : 216.
  • 5Kenter GG, Hellebrekers BW, Zwinderman KH, et al. The case for completing the lymphadenectomy when positive lymph nodes are found during radical hysterectomy for cervical carcinoma[J].Acta Obstet Gynecol Scand, 2000, 79 (1): 72.
  • 6Philippe Morice, Damienne Castaigne, Patricia Pautier, et al. Interest of pelvic and paraaortic lymphadenectomy in patients with stage IB and II cervical carcinoma [J].Gynecologic Oncology, 1999, 73 (1) : 106.
  • 7Shingleton HM. Surgery for cervical cancer: a time for reassessment[J]. Gynecol Oncol, 1998, 69 (1) : 82131.
  • 8Noriaki Sakuragi. Up - to - date management of lymph node metastasis and the role of tailored lymphadenectomy in cervieal cancer[J].Int J ClinOneol, 2007, 12 (1): 165.
  • 9Delgado G, Bundy BN, Fowler WC Jr, et al. A prospective surgical pathological study of stage I squamous carcinoma of the cervix : a Gyne- cologic Oncology Group study[J].Gynecol Oncol, 1989, 35 (4) : 314.
  • 10Buchsbaum HJ. Extra pelvic lymph node metastasis in cervical carcino- ma[J]. Am J Obstet Gynecol, 1979, 135 (10) : 814.

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