期刊文献+

左室射血分数正常的心力衰竭患者血清糖类抗原125与B型脑钠肽及心功能相关性研究

下载PDF
导出
摘要 目的探讨左室射血分数(LVEF)正常的心力衰竭(HFNEF)患者血清糖类抗原125(CA125)与B型脑钠肽(BNP)水平的相关性,以及与心功能指标的关系。方法本院慢性心力衰竭患者EF>50%的60例设为HFNEF组,EF≤50%的60例设为HFREF组,选择同期住院患者30例为对照组,分别检测血清CA125、血浆BNP浓度,并用超声心动图检测LVEF、左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)。结果 CA125、BNP、LVEDD、LVE S D水平由对照组、H F N E F组、H F R E F组依次升高,LVE F依次降低,H F N E F组与对照组比较,除LV ED D及LVESD外余差异有统计学意义;HFNEF组与HFREF组比较,除CA125外余差异有统计学意义。HFNEF组CA125与BNP呈正相关;HFREF组CA125与BNP、LVESD呈正相关,与EF呈负相关。结论 CA125与BNP及心功能指标密切相关,联合应用可早期诊断HFNEF。
出处 《中国乡村医药》 2015年第23期29-30,共2页
  • 相关文献

参考文献4

二级参考文献22

  • 1胡春松,魏云峰,朱文玲,徐进,YoonYS,罗伟,LosordoDW.心力衰竭患者血清CA125、CA19-9水平变化及意义[J].中国分子心脏病学杂志,2005,5(1):415-417. 被引量:15
  • 2The Criteria Committee of New York Heart Association 1994 revisions to classlfication of functional capacity and objective assessment of patients with disease of the heart circulation [R], 1994, 90: 644-645.
  • 3Nagele H, Bahlo M, Klapdor R, et al. CA125 and its relation to cardiac function [J]. Am Heart J, 1999, 137 (6) : 1044-1049.
  • 4Kubonishi I , Bandobashi K, MUrata N , et al . High serum levels CA125 and interleukin-6 in patient with Ki-1 lymphoma [J]. Br J Haematol, 1997, 98 (2) : 450-452.
  • 5Deleuw PW, Kroon AA. Hypertension and the development of heart failure [J]. Cardiovase Phamacol, 1998, 32 (1): 9-15.
  • 6Turk HM , Pekdemir H , BuyuberberS , et al . Serum CA125 level sin patient s with chronic heart , failure and accompanyjng pleural fluid[J]. TumorBiol , 2003 , 24 (4) : 172-175.
  • 7Vanderheyden M,Bartunek J,Goethals M,et al.Brain and other natriuretic peptides:molecular aspects[J].Eur J Heart Fail,2004;6(3):261-8.
  • 8Goenning BA,Nillsson JC,Sondergaard L,et al.Evaluation of impaired left ventricular ejection fraction and increased dimensions by multiple neurohumoral plasma concentrations[J].Eur J Hear Fail,2001;3(6):699-708.
  • 9Silvet H,YoungXu Y,Walleigh D,et al.Brain natriuretic peptide is elevated in outpatients with atrial fibrillation[J].Am J Cardio1,2003;92:1124-7.
  • 10Yamaguchi H,Yoshida J,Yamamoto K,et al.Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophy[J].J Am Coll Cardiol,2004;43(1):55-60.

共引文献32

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部