艾滋病病毒母婴传播阻断的应用效果评估

The Application Effect Evaluation of HIV Mother-to-child Transmission(PMTCT) Blocking

目的探讨对艾滋病病毒采取母婴传播阻断的应用效果。方法选取我院2011~2014年收治的感染艾滋病病毒孕妇86例,将其随机分为对照组和观察组,每组43例,其中对照组孕妇不采取任何母婴阻断措施,观察组孕妇采取综合性母婴阻断措施,将两组孕妇所产新生儿的各项数据进行对比。结果观察组新生儿不良反应发生率、12个月和18个月后的艾滋病病毒阳性率均低于对照组新生儿,且观察组新生儿的存活率和1年后死亡率与对照组新生儿对比,数据对比差异统计学有意义（P〈0.05）。结论母婴传播阻断措施可有效减少新生儿感染艾滋病病毒发生率,减少新生儿不良反应发生,对提高新生儿的生存率具有非常重要的意义。

Objective To study on HIV mother-to-child transmission（PMTCT） blocking the application effect. Methods Our hospital in 2011 to 2014 were infected with HIV,86 cases of pregnant women,and randomly divided into control group and observation group,43 cases in each group,the control group of pregnant women do not take any maternal and child block measures,observation group of pregnant women take comprehensive maternal and child block measures,the two groups of pregnant women by comparing the data of the newborn. Results The incidence of adverse reactions of newborn babies,observing group,12 months and 18 months after neonatal HIV positive rate were lower than control group,and group of neonatal mortality compared with control group the newborn survival rates and 1 years later,all have significant advantage,data compared significant difference（P〈0.05）,in statistical sense. Conclusion Maternal transmission blocking measures can effectively reduce the incidence of newborns infected with HIV,reduce the neonatal adverse reactions occur,and to improve the neonatal survival rate has very important significance.