188例心房颤动患者并发卒中的治疗分析

Analysis on Stroke and Therapy of 188 patients with Atrial Fibrillation

目的分析心房颤动（AF）患者的卒中分级情况及抗栓药物的使用情况,为更好防控AF卒中事件提供参考与依据。方法选取2010-2014年南方燕岭医院住院的188例AF患者临床资料进行回顾性分析。结果 1本研究65.96%AF患者合并脑卒中;266.94%AF患者的脑卒中为1至2个功能区梗塞及腔隙性脑梗死;3AF合并血小板偏高者脑卒中比例占90%;426.06%AF患者使用了华法林抗凝治疗;5华法林的最终调定剂量最多使用1.875 mg/d;6INR达标比例7.28%。结论 1社区住院AF患者脑卒中比例较高;2住院AF患者的脑卒中程度以1~2个功能区梗塞或腔隙性脑梗死为主;3AF合并血小板偏高者脑卒中比例较高;4抗栓治疗仍然不规范;5临床可以1.875~2.5mg/d作为华法林抗凝的起始剂量;6INR达标比例相当低。

Objective To analyze the stroke and antithrombotic therapy of 188 patients with atrial fibrillation（ AF）. Methods The clinical data of AF patients in Nanfang-Yanling Hospital during 2010-2014 were analyzed retrospectively。Results 165. 96% patients with AF suffer from stroke. 266. 94% stroke patients with AF were 1 or 2 parts of the stroke and lacunar cerebral infarction. 390% patients with AF combine thrombocytosis suffer from stroke. 4 Only 26. 06% patients with AF use warfarin. 5 The dosage of adjustive warfarin in the end is 1. 875 mg daily. 67. 28% patients with AF were up to INR standard. Conclusion 1 patients with AF suffer from stroke seriously. 2 stroke patients with AF were mainly 1 or 2 area stroke and lacunar cerebral infarction. 3patients with AF and high platelet suffer from stroke seriously. 4 patients with AF use warfarin rarely. 51. 875 ~ 2. 5 mg daily can be used in clinical as the starting dose of warfarin anticoagulant therapy. 6 patients with AF were up to INR standard rarely.