平抽方治疗儿童多发性抽动症的临床疗效研究

Clinical Effect of Tics-pacifying Formula on Multiple Pedo-tics

目的:评价平抽方治疗小儿多发性抽动症的临床疗效。方法:60例同时合并有上感症状,临床诊断为小儿抽动症患者,辨证分型为"风热犯肺""肝风内动"以平抽方加减治疗,4周为1疗程,共治疗12周,以中医证候评分量表(TCMSSS)、耶鲁抽动严重程度量表(YGTSS)评估治疗疗效。结果:平抽方在治疗终点12周时,中医症候评分100%有效,耶鲁评分改善率也达到95%,治疗前后两者的评分比较,疗效显著(P=0.000),相关分析显示发病年龄与治疗改善率呈负相关(P=0.01,0.03),年龄越小,治疗效果越显著。结论:平抽方能显著改善风热犯肺、肝风内动型多发性抽动患者的抽动症状,对抽动症患者尽早治疗,疗效更好。

Objective： to evaluate the clinical effect of Tics-pacifying Formula on multiple pedo-tics. Methods： 60 cases with pedo-tics with URTI,classified as wind-heat invading lung and liver-wind stirring,were treated with modified Tics-pacifying Formula,4weeks as a course for 12 weeks. TCMSSS and YGTSS were used to evaluate the curative effect. Results： at the 12 th week,the effective rate was 100% with TCMSSS,and 95% with YGTSS; compared with results before and after treatment,the difference was significant（ P = 0. 000）; correlation analysis showed that age of onset was negatively correlated with the improvement rate of treatment（ P =0. 01,0. 03）. Conclusion： Tics-pacifying Formula can significantly improve the symptoms in patients with multiple tics. The early the treatment is,the better the effect will be.