原发性高血压患者脑电值与觉察压力的关系

Relationship between Electroencephalogram and Perceived Stress in Essential Hypertension Patients

目的了解原发性高血压患者脑电值与觉察压力的关系,为临床高血压的防治提供理论依据。方法以60例汉族高血压住院患者为研究组,60例性别、年龄等与研究组相匹配汉族健康个体为对照组,以心算任务为应激源,测量并记录其在基线期、任务期、恢复期的脑电参数值(θ、α、感觉运动节律、β),指导被试对象填写觉察压力量表。结果研究组和对照组在应激中的脑电θ值比较差异有统计学意义(t=4.01,P=0.048)。研究组应激后θ波动值与觉察压力量表的控制感维度相关(r=-0.26,P=0.044)。以"控制感"得分为因变量,以研究组应激后θ波动值为自变量,进行回归分析,变量选入标准为P≤0.05,剔除标准为P≥0.01,结果显示研究组应激后θ波动值满足进入方程要求,能解释"控制感"维度的5.2%。结论原发性高血压患者在压力情境下,与其睡眠和创造性相关的脑电θ值降低,因无法对压力事件进行控制而产生的压力感觉增强。

Objective To explore the relationship between electroencephalogram and perceived stress in Chinese essential hypertension（ EH） patients. Methods Totally 60 EH patients were enrolled as the case group,and 60 gender-and age-matched healthy subjects as the control group. Graded mental arithmetic was used as a psychological stressor. The physiological values of electroencephalogram（ Theta, Alpha, sensorimotor rhythm,and Beta） were recorded at baseline and in mission period and recovery period. Subjects were instructed to complete the Perceived Stress Scale. Results The electroencephalogram Theta value was significantly different between the case group and the control group（ t = 4. 01,P = 0. 048）. In the case group,the fluctuating Theta value was correlated with the control dimension in the Perceived Stress Scale（ r =- 0. 26,P = 0. 044）. Also in the case group,with the score of ＂sense of control＂as the dependent variable and the fluctuating value of Thetaafter stress as the independent variables,regression analysis was performed. The opt-in standard was≤0. 05 and the culling standard was≥0. 01. The results shows that the fluctuating value of Theta after stress in the case group met the requirements to enter the equation and could explain 5. 2% of＂sense of control＂dimension. Conclusion The Theta values associated with the sleeping and creativity decrease under stressful situations in EH patients following the increaed sense of pressure due to failure in controlling the pressure events.