10种晋产野生黄芩根中黄芩苷、黄芩素与汉黄芩素含量比较

Determination of Baicalin,Baicalein and Wogonin in Ten Wild Scutellaria baicalensis from Shanxi

采用高效液相色谱法对山西省10个产地野生黄芩根中主要有效成分黄芩苷、黄芩素和汉黄芩素含量进行了测定分析。结果表明,10种晋产野生黄芩根中主要有效成分含量差异明显,黄芩苷的含量为5.79%~15.31%,黄芩素的含量为0.49%~2.28%,汉黄芩素的含量为0.07%~0.42%。黄芩苷含量与纬度高低呈负相关。山西北部朔州市右玉县沟北村与山阴县西郭家窑村的野生黄芩根中黄芩苷含量低于《中国药典》规定的8.0%,山西东南部晋城市陵川县瓦窑上村的野生黄芩根中黄芩苷含量则高达15.31%。山西中西部吕梁市交城县双家寨村的野生黄芩根中黄芩素和汉黄芩素含量均为最高,分别为2.28%和0.42%。

In this study, the content of main effective ingredients including baicalin, baicalein and wogonin of wild Scutellaria baicalensis from 10 areas of Shanxi were investigated by HPLC, The results showed that：there was a significant difference in the content of balcalin, baicalein and wogonin in 10 samples of ScuteUaria. The content of baicalin, baica- lein and wogonin were 5.79% -15.31% ,0.49% -2.28% and 0.07% -0.42% ,respectively. The content of baicalin had positive correlation with the cultivation latitude of S. baicalensis, the content of baicalin in S. baicalensis samples from Goubei country,Youyu county and Yinliangshan,Shanyin county was not match up with the standard （8.0%） required by Chinese Pharmacopoeia,while the content of baicalin from Wayaoshang country, Linchuan county was determined to be 15.31%. The content of baicalein and wogonin from Suangjiazhai country,Jiaocheng county was determined to be 2. 28% and 0.42%.