摘要
建立了超高效液相色谱-串联质谱（UPLC-MS／MS）同时测定饮品中安赛蜜、糖精钠、甜蜜素、阿斯巴甜、阿力甜、纽甜、三氯蔗糖的分析方法，对白酒、葡萄酒、果汁3种样品进行了分析．样品经稀释后，13000r／min高速离心10min，以5mmol／L甲酸铵缓冲溶液／甲醇为流动相，梯度洗脱．在优选条件下，方法线性范围为10～500μg/L，线性相关系数R。不低于0．9981，检出限（S／N=3）为0．003～8μg/L，样品回收率为77．10％～118．94％，7种化合物测定结果的相对标准偏差（RSD）为0．19％～5．24％．方法操作简便，灵敏度高，适用于3种基质中7种人工合成甜味剂的快速检测．
The method for determination of 7sweeteners in wine, grape wine and juice has been developed using the ultra performance liquid chromatography-tandem mass spectrometry （UPLC- MS/MS） with ammonium acetate solution/methanol as the mobile phase. Prior to centrifuge with 13 000 r/min for 10 rain, samples were diluted. Under optimized conditions, the limits of detection （ LOD, S/N = 3 ） were from 0. 003 to 8 μg/L and the linear range was between 10 and 500 Ixg/L with R2 ≥0. 998 1. Recoveries were in the range of 77.10% - 118.94%, and RSDs of the peak areas were between 0.19% and 5.24%. This method is simple, sensitive and reliable, and is suitable for the rapid detection of artificial sweeteners in these three drinks.
出处
《分析测试技术与仪器》
CAS
2015年第4期218-224,共7页
Analysis and Testing Technology and Instruments
