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胎儿单脐动脉的研究进展 被引量：4

Research progress of fetal single umbilical artery
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摘要 正常胎儿的脐带有2条脐动脉,而单脐动脉(SUA)胎儿的脐带中仅为1条脐动脉,系脐带发育及结构异常。SUA的诊断主要依靠产前超声检查和产后胎盘、脐带大体检查及其病理学检查。目前,SUA的发生机制尚未阐明。越来越多的研究结果显示,SUA是胎儿先天畸形、染色体核型异常、早产及低出生体质量的软标记,SUA亦可能引起胎儿宫内生长受限及出生后生长发育不良等不良结局。笔者拟就SUA的概念及分类、诊断、发生机制、与之相关的胎儿畸形和染色体核型异常等综述如下。 Normal umbilical cord have two umbilical artery,however,only one in the single umbilical artery（SUA）fetus.The diagnose of SUA relies mainly on ultrasound,the gross examination and pathological examination for placenta and umbilical cord after labor.Currently,the cause and mechanism of SUA are still unclear.More and more literatures indicate that SUA is a soft maker for fetal malformation,chromosome abnormality,preterm labor and low weight.SUA may lead to some bad outcomes,such as intrauterine growth restriction and retarded growth.This review focuses on the diagnosis,mechanism,relative fetal malformations and chromosome abnomality of SUA.
作者 邓春艳 王晓东 余海燕
机构地区 四川大学华西第二医院妇产科
出处 《中华妇幼临床医学杂志（电子版）》 CAS 2015年第6期786-788,共3页 Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金 教育部留学回国人员科研启动基金(2102940-15-13) 四川省科技支撑计划项目(2011SZ0195)~~
关键词 单脐动脉 诊断 先天畸形 染色体畸变 胎儿 Single umbilical artery Diagnosis Congenital abnormalities Chromosome aberrations Fetus
分类号 R714.5 [医药卫生—妇产科学]
  • 相关文献

参考文献24

  • 1Gornall AS, Kurinczuk JJ, Konje JC. Antenatal detection of a single umbilical artery: does it matter? [J]. Prenat Diagn, 2003, 23(2) : 117-123.
  • 2Geipel A, Germer U, Welp T, et al. Prenatal diagnosis of single umbilical artery: determination of the absent side, associated anomalies, Doppler findings and perinatal outcome[J]. Ultrasound Obstet Gynecol, 2000, 15(2): 114-117.
  • 3李胜利.胎儿畸形产前超声诊断学[M].北京:人民军医出版社,2007:550.
  • 4Khalil MI, Sagr ER, Elrifaei RM, et al. Outcomes of an isolated single umbilical, artery in singleton pregnancy: a large study from the Middle East and Gulf region[J]. Eur J Obstet Gynecol Reprod Biol, 2013, 171(2): 277-280.
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  • 6Martinez-Payo C, Gaitero A, Tamarit I, et al. Perinatal results following the prenatal ultrasound diagnosis of single umbilical artery[J]. Acta Obstet Gynecol Scand, 2005, 84 (11) : 1068- 1074.
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二级参考文献11

  • 1Gornall AS, Kurinczuk JJ, Konje JC. Antenatal detection of a single umbilical artery: Does it matter[J]? Prenat Diagn, 2003, 23 (2):117-123.
  • 2Granese R, Coco C, Jeanty P. The value of single umbilical artery in the prediction of fetal aneuploidy: Findings in 12,672 pregnant women[J]. Ultrasound Q, 2007, 23(2):117-121.
  • 3Burshtein S, Levy A, Holcberg G, etal. Is single umbilical artery an independent risk fact for perinatal mortality[J]? Arch Gynecol Obstet, 2011, 283(2):191-194.
  • 4Persntte WH, Hobbins J. Single umbilical artery: A clinical enigmain modern prenatal diagnosis [J ]. Ultrasound Obstet Gynecol,1995,8(2) :216-229.
  • 5Mu SC, Lin CH, Chen YL, et al. The perinatal outcomes of asymptomatic isolated single umbilical artery in full-term neonates [J]. Pediatr Neonatol,2008, 49(6) :230-233.
  • 6Suess G, Raio L, Kuhn A, et al. Arterial-adaptive dilatation and Doppler velocimetry in normal fetuses with a single umbilical artery[J]. Ultraschall Med, 2009, 30 (5) : 485-489.
  • 7Cristina MP,Ana G, In6s T, et al. Perinatal results following the prenatal ultrasound diagnosis of single umbilical artery[J]. Acta Obstet Gynecol Scand, 2005, 84 (11) : 1068-1074.
  • 8Dagklis T, Defigueiredo D, Staboulidou I, et al. Isolated single umbilical artery and fetal karyotype [-J ]. Ultrasound Obstet Gynecol,2010, 36(3):291-295.
  • 9Chetty-John S, Zhang J, Chen Z, et al. Long-term physical and neurologic development in newborn infants with isolated single umbilical artery[J]. Am J Obstet Gyneeol,2010, 203(4) :368. e1- e7.
  • 10Deshpande SA, Jog S, Watson H, et al. Do babies with isolated single umbilical artery need routine postnatal renal ultrasonography[J]? Arch Dis Child Fetal Neonatal Ed, 2009, 94 (4): F265-267.

共引文献23

同被引文献26

引证文献4

二级引证文献10

中华妇幼临床医学杂志（电子版）
2015年 第6期

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