基于MRI ROI三维重建体积测量法对头颈静脉畸形血管内硬化治疗的疗效评估

Efficacy Evaluation of Sclerotherapy for Venous Malformations on Head and Neck Region Based on ROI-volumentry of MRI Assessment by Three-dimensional Reconstruction Measurement

目的采用MRI ROI三维重建体积测量法,评价头颈部静脉畸形血管内硬化治疗的疗效。方法对2012年10月到2015年3月,在我科接受治疗、MRI数据合格的18例头颈部局限型静脉畸形患者进行回顾性分析。18例患者行头颈部经皮穿刺血管内硬化治疗1~2次,A组11例患者注入无水乙醇,B组7例患者注入聚桂醇泡沫,治疗前后行MRI检查。随访2~30个月,将MRI数据导入Mimics18.0软件,选取MRI ROI的静脉畸形阈值范围,计算出治疗前后静脉畸形体积减少百分率,用静脉畸形血管内硬化治疗评价标准分析数据。结果基于MRI ROI三维重建体积测量法和静脉畸形血管内硬化治疗评价标准,18例患者中,A组有效率为91%,B组有效率为86%。结论 MRI ROI三维重建体积测量法,能评价头颈部静脉畸形血管内硬化治疗的疗效,具有良好的临床实用性,值得推广。

Objective To evaluate the efficacy of sclerotherapy for venous malformations（VMs） on head and neck region using ROI（region of interest） volumentry of MRI assessment by three-dimensional reconstruction measurement. Methods A retrospective analysis was selected, composed of 18 patients with VMs and fully qualified MRI data from October 2012 to March 2015. All patients were treated with sclerotherapy either once or twice and were divided into two groups. Percutaneous sclerotherapy was performed by direct injection of Ethanol（group A, n=11） and Polidocanol foam sclerosants（group B, n=7）.Patients underwent MRI before and after sclerotherapy. All the patients were followed up for 2 to 30 months after treatment.The MRI data was imported into Mimics18.0 software. The threshold ranges of VMs in ROI MRI were selected. The regression rates of lesions were compared before and after sclerotherapy. And the results were evaluated by the response evaluation criteria in VMs. Results According to the ROI-volumentry of MRI assessment by three dimensional reconstruction measurement and the response evaluation criteria in VMs, the effective rate in Group A was 91%, and 86% in Group B. Conclusion The method of ROI-volumentry of MRI assessment by three-dimensional reconstruction measurement can reflect and evaluate the regression rates of the lesions after sclerotherapy for patients with VMs on head and neck region.Our expertence demonstrate the high practicability and potential of this method.