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阑尾神经内分泌肿瘤11例临床病理学分析 被引量:3

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摘要 目的探讨阑尾神经内分泌肿瘤的临床病理学特征。方法对11例阑尾神经内分泌肿瘤进行临床资料分析、组织学观察和免疫组化及特殊染色,并复习相关文献。结果11例中男性6例,女性5例,年龄30~68岁。肿瘤直径均≤1 cm,位于阑尾顶端8例,顶端及体部2例,体部1例。11例中神经内分泌瘤1级9例,杯状细胞类癌2例。Syn阳性10例,Cg A阳性8例,Ki-67增殖指数均〈2%。AB染色阳性2例。结论阑尾神经内分泌肿瘤临床缺乏特异性,规范检查大体标本并合理应用免疫组化和特殊染色有助于确诊。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2015年第12期1419-1421,共3页 Chinese Journal of Clinical and Experimental Pathology
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参考文献13

  • 1中国胃肠胰神经内分泌肿瘤病理学诊断共识[J].中华病理学杂志,2011,40(4):257-262. 被引量:291
  • 2Deschamps L, Couvelard A. Endocrine tumors of the appendix: a pathologic review[J]. Arch Pathol Lab Med, 2010,134(6) :871 -5.
  • 3Bosman F T, Carneiro F, Hruban R H, et al. World Health Or- ganization classification of tumors of the digestive system[M]. Ly- on: IARC Press, 2010:13 -4.
  • 4Volante M, Daniele L, Asioli S, et al. Tumor staging but not grad- ing is associated with adverse clinical outcome in neumendocrine tumors of the appendix: a retrospective clinical pathologic analysis of 138 cases[J]. Am J Surg Pathol, 2013,37(4) :606 - 12.
  • 5余英豪,陈远清.阑尾神经内分泌肿瘤WHO分类及其临床病理实践[J].临床与实验病理学杂志,2014,30(11):1203-1205. 被引量:8
  • 6Johannesen E, Nguyen V. WHO grade 2 neuroendocrine tumor in a 15-year-old male: a case report and literature review~ J]. Case Rep Pathol, 2014,2014:426161.
  • 7Mitra B, Pal M, Paul B, et al. Goblet cell carcinoid of appendix : a rare case with literature review[ J]. Int J Surg Case Rep, 2013, 4(3) :334 -7.
  • 8Tang L H. Epithelial neoplasms of the appendix[ J]. Arch Pathol Lab Med, 2010,134(11) :1612 -20.
  • 9Ploenes T, Bomer N, Kirkpatrick tumour, mucinous ad C J, et al. Neuroendocrine and signet-ring cell carcinoma of the appendix : three cases and review of literature [ J ]. Indian J Surg, 2013,75 ( Suppl 1 ) :299 - 302.
  • 10Mourra N, Scriva A, Mansiaux Y, et al. Clusterin expression in gastrointestinal neuroendocrine tumours is highly correlated with lo- cation and is helpful in determining the origin of liver metastases [ J]. Histopathology, 2014,65 (5) :642 - 50.

二级参考文献28

  • 1Yaov JC,Hassan M,Phan A,et al.One hundred years after "carcinoid ":epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States.J Clin Oncol,2008,26(18):3063-3072.
  • 2Yao JC,Shah MH,Ito T,et al.Everolimus for advanced pancreatic neuroendocrine tumors.N Engl J Med,2011,364(6):514-523.
  • 3Raymond E,Dahan L,Raoul JL,et al.Sunitinib malate for the treatment of pancreatic neuroendocrine tumors.N Engl J Med,2011,36(6):501-513.
  • 4Kl(o)ppel G,Couvelard A,Perren A,et al.ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors:towards a standardized approach to the diagnosis of gastroenteropancreatic neuroendocrine tumors and their prognostic stratification.Neuroendocrinology,2009,90 (2):162-166.
  • 5Klimstra DS,Modlin IR,Adsay NV,et al.Pathology reporting of neuroendocrine tumors:application of the Delphic consensus process to the development of a minimum pathology data set.Am J Surg Pathol,2010,34(3):300-313.
  • 6Bosman FT,Carneiro F,Hruban RH,et al.WHO classification of tumours of the digestive system.Lyon:IARC Press,2010.
  • 7Oberndorfer S.Karzinoide tumoren des dunndarms.Frankf ZPatrol,1907,1:426-432.
  • 8Williams ED,Siebenmann RE,Sobin LH.Histological typing of endocrine tumours.Geneva:World Health Organization,1980.
  • 9Hamilton SR,Aaltonen LA.World Health Organization classification of tumours.Pathology and genetics of tumours of the digestive system.Lyon:IARC Press,2000.
  • 10Rindi G,Kl(o)ppel G,Alhman H,et al.TNM staging of foregut (neuro) endocrine tumors:a consensus proposal including a grading system.Virchows Arch,2006,449(4):395-401.

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