2Chong CR,Xu J,Lu J,et al.Inhibition of angiogenesis by the antifungal drug itraconazole[J].ACS Chem Biol,2007,2(4):263-270.
3Xu J,Dang Y,Ren YR,et al.Cholesterol trafficking is required for m TOR activation in endothelial cells[J].Proc Nat1 Acad Sci USA,2010,107(10):4764-4769.
4Aftab BT,Dobromilskaya I,Liu JO,et al.Itraconazole inhibits angiogenesis and tumor growth in non-small cell lung cancer[J].Cancer Res,2011,71(21):6764-6772.
8Lear JT.Oral hedgehog-pathway inhibitors for basal-cell carcinoma[J].N Engl J Med,2012,366(23):2225-2226.
9Kim J,Aftab BT,Tang JY,et al.Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists[J].Cancer Cell,2013,23(1):23-34.
10Kim J,Tang JY,Gong R,et al.Itraconazole,a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth[J].Cancer Cell,2010,17(4):388-399.
