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降钙素原及C反应蛋白水平对重症肺炎预后的评估 被引量:18

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摘要 目的:探讨降钙素原(PCT)及C反应蛋白(CRP)水平在重症肺炎患者预后判断及转归中的作用。方法:回顾性分析65例重症肺炎患者的临床病历资料,分为死亡组(29例)和存活组(36例),对比2组的临床特征、治疗前、入院后48、72 h、出院前或死亡前血PCT、CRP水平及APACHEⅡ评分。结果:2组患者血PCT、CRP水平均较正常值明显升高,其中死亡组血PCT、CRP水平较存活组明显升高(P〈0.01)。抗生素使用有效时血PCT水平明显降低,而血CRP水平下降速度较PCT慢。血清PCT水平与APACHEⅡ评分的相关系数高于CRP(r分别为0.689、0.432)。血PCT和CRP水平升高与患者死亡相关,OR值(95%CI)分别为2.9(1.2~7.8)、7.4(3.5~18.7)(P〈0.05)。结论:血PCT和CRP水平对判断重症肺炎患者预后及转归有较好的作用,其中血PCT优于CRP水平。
出处 《内科急危重症杂志》 2015年第6期443-444,共2页 Journal of Critical Care In Internal Medicine
基金 常州市科技计划项目(No:WZ2010-21)
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参考文献7

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二级参考文献33

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