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Synthesis of 1,2,3-benzotriazin-4-one derivatives containing spirocyclic indoline-2-one moieties and their nematicidal evaluation 被引量:3

Synthesis of 1,2,3-benzotriazin-4-one derivatives containing spirocyclic indoline-2-one moieties and their nematicidal evaluation
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摘要 To discover new chemotypes of nematicides with proper toxicological profiles, a series of novel 1,2,3-benzotriazin-4-one derivatives were synthesized and further bioevaluated. The bioassay results showed that most of the synthesized compounds were endowed with moderate to good control efficacy against Meloidogyne incognita at 10.0 mg/L in vivo. Among them, compounds 6k and 6p displayed 100%inhibitory activities at this concentration, which implied that they could be used as lead compounds for promising nematicides. To discover new chemotypes of nematicides with proper toxicological profiles, a series of novel 1,2,3-benzotriazin-4-one derivatives were synthesized and further bioevaluated. The bioassay results showed that most of the synthesized compounds were endowed with moderate to good control efficacy against Meloidogyne incognita at 10.0 mg/L in vivo. Among them, compounds 6k and 6p displayed 100%inhibitory activities at this concentration, which implied that they could be used as lead compounds for promising nematicides.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2015年第12期1502-1506,共5页 中国化学快报(英文版)
基金 financial supported by the National High Technology Research and Development Program of China(National 863 Program,No.2013AA065202) the National Natural Science Foundation of China(No.21272071) supported by the Special Fund for Agro-scientific Research in the Public Interest(No.201103007) the Fundamental Research Funds for the Central Universities
关键词 Meloidogyne incognita displayed endowed moderate implied potent crops removed afford Meloidogyne incognita displayed endowed moderate implied potent crops removed afford
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