摘要
目的观察小青龙汤治疗肺气虚寒型变应性鼻炎(allergic rhinitis,AR)的疗效。方法采用随机对照方法将符合纳入标准的128例肺气虚寒型AR患者,随机分为中药组(小青龙汤)及西药组各64例,各以小青龙汤或是西药阶梯化治疗4周,以视觉模拟量表(VAS)及鼻眼结膜相关生活质量问卷调查量表(RQLQ)衡量患者AR症状及生活质量改善情况。结果组内对照比较结果显示,各组VAS、RQLQ评分在治疗前及治疗后16周的差异均具有统计学意义(P<0.05)。治疗后16周,组间VAS评分差异无统计学意义(P>0.05),但RQLQ评分差异具有统计学意义(P<0.05)。两组均无严重不良反应事件发生。结论小青龙汤和西药的阶梯化治疗均有利于改善AR患者症状及生活质量。临床实践中需根据患者的病情和证型,选用多学科指导下的科学系统序贯的个体化治疗。
Objective To observe the efficacy of Xiao-qing-long-tang in the treatment of allergic rhinitis(AR)with lung-qi deficiency and cold syndrome.Methods 128 patients with lung-qi deficiency and cold syndrome were randomized to either the Xiao-qing-long-tang(group A,n=64)or the conventional medicine(group B,n=64)group and received their respective treatment for 4consecutive weeks.Their improvement in quality of life was measured through visual analogue scale(VAS)and rhinoconjunctivitis quality of life questionnaire(RQLQ).Results The VAS and RQLQ scores for both groups were significantly improved after treatment(P 0.05). When compared laterally after 16 weeks of treatment,there was no statistically significant difference between two groups in terms of VAS scores(P〈0.05),while improvement in RQLQ scores in group B was better than group A,the difference of which was statistically significant(P〈0.05).No serious side effect was found in both groups.Conclusion Both Xiao-qing-long-tang and conventional medicine can improve the symptoms and the quality of life of AR patients.In clinical practice,multidisciplinary sequential and personalized therapy is recommended according to patient′s condition and syndrome.
出处
《成都医学院学报》
CAS
2015年第6期696-699,共4页
Journal of Chengdu Medical College
基金
国家十二五科技支撑计划项目(No:2015BAI04B00)
四川省国际科技合作与交流研究计划项目(No:2013HH0021)
关键词
小青龙汤
肺气虚寒证
变应性鼻炎
Xiao-qing-long-tang
Allergic rhinitis
Lung-qi deficiency and cold syndrome