社区2型糖尿病人群耐甲氧西林金黄色葡萄球菌携带率及其危险因素研究

Nasal colonization prevalence and risk factors of methicillin-resistant staphylococcus aureus in type 2 diabetic patients from communities

目的:了解社区2型糖尿病人群耐甲氧西林金黄色葡萄球菌(MRSA)的携带情况及其影响因素。方法:采用横断面研究设计,随机抽取佛山市里水镇11个社区的2型糖尿病患者,以调查问卷收集患者相关信息并采集2型糖尿病患者的鼻拭子样本进行细菌的分离鉴定。结果:共调查了417例2型糖尿病患者,金黄色葡萄球菌的携带率为10.31%,MRSA的携带率为5.28%。金黄色葡萄球菌携带与2型糖尿病人群患病年限有关(P=0.003),MRSA携带与体质指数(BMI)有关(P=0.017)。结论:该地区2型糖尿病人群MRSA携带率较高,患糖尿病年限是金黄色葡萄球菌携带的一个重要影响因素,BMI对于2型糖尿病人群是否携带MRSA具有重要意义。

Objective To determine the nasal colonization prevalence and risk factors of methieillin- resistant staphylococcus aureus （MRSA） in the type 2 diabetic patients from the communities. Methods Crosssectional study and random sampling method were conducted to enroll patients with type 2 diabetic patients from 11 communities of Foshan Lishui. Epidemiologic risk factors were obtained by pre-designed questionnaires and anterior nares swabs were collected for identifying MRSA. Results A total of 417 type 2 diabetic patients were enrolled in the study. The prevalences of staphylococcus aureus and MRSA were 10.31% and 5.28% , respectively. Clinical duration of diabetes was significantly associated with staphylococcus aureus colonization （P= 0.003） and body mass index （BMI） was an independent risk factor for MRSA colonization （P=0.017）. Conclusion The nasal carriage rate of MRSA was high among the patients with type 2 diabetes in the communities. Independent risk factor for staphylococcus aureus colonization is clinical duration of diabetes and so is BMI for MRSA colonization.