摘要
目的黄芩苷不同亲和力和选择性分子印迹聚合物的制备及其评价。方法以黄芩苷(Baicalin,BA)为模板分子,分别通过沉淀聚合、纳米二氧化硅表面聚合和介孔分子筛表面聚合法合成不同的黄芩苷分子印迹聚合物。采用透射电镜对印迹聚合物的形态和结构进行表征,通过动态吸附和静态吸附实验研究了不同方法合成的印迹聚合物的吸附能力。结果不同结构的黄芩苷分子印迹聚合物制备成功且介孔分子筛表面分子印迹聚合物对黄芩苷具有最强的吸附能力。结论黄芩苷分子印迹聚合物为从复杂样品中高效分离富集黄芩苷提供新材料。
Objective To prepare and evalute different baicalin（BA） molecularly imprinted polymers with affinity and selectivity to BA. Methods Baicalin（BA） as template, different kinds of selective recognition of baicalin molecularly imprinted polymers were prepared. The surface morphologies and characteristics of the MIPs were characterized transmission electron microscope（TEM）. The adsorption properties of polymer microsphere for the template were tested by the dynamic adsorption equilibrium experiments and static adsorption equilibrium experiments. Results The experiment showed that the imprinting process was sucessfully and the molecularly imprinted mesoporous silica polymers（MIP@SBA-15） have higher adsorbed amount than the others. Conclusion All these polymers provide some new methods for the efficient separation and enrichment of baicalin from complex samples.
出处
《现代中药研究与实践》
CAS
2015年第6期48-51,55,共5页
Research and Practice on Chinese Medicines
基金
国家自然科学基金(30801558
81373895
81173538)
关键词
分子印迹聚合物
黄芩苷
吸附特性
介孔分子筛
molecular imprinting polymer
baicalin
adsorption characteristic
mesoporous silica
