肠梗阻导管联合奥曲肽治疗粘连性肠梗阻的疗效观察

Observation on the curative effect of intestinal obstruction catheter complex combined with octreotide in the treatment of adhesive intestinal obstruction

目的:观察肠梗阻导管联合奥曲肽治疗粘连性肠梗阻的临床疗效。方法:收集78例确诊为粘连性肠梗阻的患者,用随机数字表将患者分为联合组、肠梗阻导管组和奥曲肽组,每组26例,3组均给予常规综合治疗,在此基础上联合组给予肠梗阻导管联合奥曲肽治疗,肠梗阻导管组给予肠梗阻导管治疗,奥曲肽组给予奥曲肽联合鼻胃管减压治疗,观察并比较3组的临床症状和疗效。结果:联合组腹痛缓解时间、恢复排气时间较肠梗阻导管组和奥曲肽组缩短,第1个24 h胃肠减压量较肠梗阻导管组减少,较奥曲肽组增加,差异有统计学意义(P<0.05或P<0.01)。联合组患者治疗总有效率(为100%)明显高于肠梗阻导管组(为84.6%)和奥曲肽组(为73.1%),3组比较差异有统计学意义(P<0.05或P<0.01)。结论:联合应用肠梗阻导管和奥曲肽能减少胃肠减压量,更快缓解粘连性肠梗阻患者的症状,增加患者治疗总有效率,临床疗效确切。

Objective： To observe the curative effect of intestinal obstruction catheter complex combined with octreotide in the treatment of adhesive intestinal obstruction. Methods： A total of 48 adhesive intestinal obstruction patients were collected and randomly divided into the combination group（16 patients）, the intestinal obstruction catheter group（16 patients） and the octreotide group（16 patients）. Three groups were all treated with the routine comprehensive therapy, while the combination group added intestinal obstruction catheter and octreotide, the intestinal obstruction catheter group added intestinal obstruction catheter and the octreotide group added octreotide and nasogastric tube. Clinical symptoms and curative effect of there groups were observed and compared.The experimental data were analyzed by statistical methods. Results： After therapy, the bloating pain relief time and recovery exhaust time in the combination group were shorter than that in other two groups. The amount of first 24 h gastrointestinal decompression of the combination group was less than the intestinal obstruction catheter group and more than the octreotide group（P〈0.05 or P〈0.01）. While the total effective rate of the combination group（100%） was higher than that of the other two groups（P〈0.05 or P〈0.01）. Conclusion： The intestinal obstruction catheter complex combined octreotide in treatment of adhesive intestinal obstruction can reduce the gastrointestinal decompression amount, relieve the clinical symptoms probiotics in the adhesive intestinal obstruction patients fastly, and increase patient treatment efficiency.