丹红注射液辅助治疗慢性肺源性心脏病急性加重期效果分析

An effective analysis of treating chronic pulmonary heart disease with the Danhong injection

目的:探讨丹红注射液辅助治疗慢性肺源性心脏病急性加重期的方法及临床疗效。方法:将2011年2月-2014年4月收治的84例慢性肺源性心脏病急性发作期患者随机分为观察组及对照组各42例,对照组给予常规综合治疗,观察组同时加用丹红注射液治疗,对两组患者临床疗效及治疗前后平均肺动脉压进行比较。结果:观察组总有效率为95.2%,对照组总有效率为83.3%,组间比较差异显著(P<0.05);治疗前对照组平均动脉压为(66.1±7.3)mm Hg,观察组为(65.9±7.1)mm Hg,组间比较无显著差异(P>0.05);治疗后对照组平均动脉压为(58.7±6.4)mm Hg,观察组为(51.6±5.7)mm Hg,组间比较差异显著(P<0.05)。结论:丹红注射液辅助治疗慢性肺源性心脏病急性加重期患者可有效降低血液黏稠度及肺动脉压力,改善呼吸循环功能,提高临床疗效。

Objective： To investigate clinical efficacy of the Danhong injection on chronic pulmonary heart disease. Methods： From February 2011 to April 2014, 84 patients were divided into the observed group and the control group, 42 cases for each. The control group was given conventional integrative treatment; the observed group was given the Danhong injection more. Clinical efficacy and mean pulmonary artery pressure in two groups were compared. Results： Total efficiency in the observed group was 95.2%; and it in the control group was 83.3%. There was a significant difference（P〈0.05）. Before treatment, mean arterial pressure in the control group was（66.1±7.3）mm Hg, and was（65.9±7.1） mm Hg in the observed group; the difference was not statistically significant（P〉0.05）. After treatment, mean arterial pressure in the control group was（58.7±6.4） mm Hg, and was（51.6±5.7） mm Hg in the observed group; The difference was statistically significant（P〈0.05）. Conclusion： The Danhong injection on chronic pulmonary heart disease could decrease blood viscosity and pulmonary artery pressure, improve respiratory and circulatory functions.