亚低温冲洗液在高血压脑出血颅内血肿冲洗中的应用体会

Application of mild hypothermia washing liquid in rinsing hypertensive intracranial hematoma

目的探讨亚低温冲洗液在高血压脑出血颅内血肿冲洗中的应用效果。方法选取观察组患者150例和对照组患者128例,观察组使用35℃亚低温冲洗液,对照组使用4℃冲洗液,记录术前及术中平均动脉压、呼吸、心率;经颅多普勒(TCD)监测术前及术中患侧大脑中动脉平均血流速度(Vm)、搏动指数(PI);复查头颅CT了解血肿的吸收。结果通过比较,对照组术中平均动脉压高于观察组,心率快于观察组;对照组术中大脑中动脉平均血流速度快于对照组(P<0.05);观察组血肿吸收好于对照组(P<0.05)。结论 35℃亚低温冲洗液较4℃冲洗液对患者生理指标影响更小,适应性好、安全性高,值得临床推广。

[Objective] To investigate the effect of mild hypothermia rinsing fluid on intracranial hematoma in patients with hypertension. [Methods] There were 150 patients in the observation group and 128 patients in the control group. The observation group used 35℃ hypothermia fluid, the control group used 4℃ rinsing fluid. The mean arterial pressure before and during operation, respiration rate and heart rate were recorded. Transcranial Doppler was used to monitor preoperative and intraoperative mean flow velocity and pulse index of ipsilateral middle cerebral artery. Head CT was used to observe hematoma absorption, [ Results] The intraoperative mean arterial blood pressure of the control group was higher than that of the observation group, the heart rate was faster than that of the observation group. The intraoperative mean flow velocity of middle cerebral artery in the control group was faster than that of the observation group （P〈 0.05）. The hematoma absorption in the observation group was better than that in the control group （P 〈 0.05）. [Conclusions] Compared with 4℃ rinsing fluid, 35℃ hypothermia fluid has less influence on patients＇ physiological indicators with good adaptability and increased safety. The clinical trial is worth promoting.