期刊文献+

把握精准医学脉络,中西医结合治疗结晶肾损伤 被引量:5

下载PDF
导出
摘要 现代医学发展日新月益,2015年初美国国情咨文宣布了一项名为精准医学计划(precision medicine initiative)的项目,精准医学(precision medicine)这一概念迅速受到全球医疗界的关注。一般来讲,精准医学是以个性化医疗为核心指导、在基因组学、蛋白质组学等大数据为支撑的医学概念与模式。其本质是通过对于大样本人群与特定疾病类型进行生物标志物的分析、鉴定及验证,从而精确寻找到疾病的原因和治疗的靶点。然后针对特定疾病的不同疾病阶段,设计个性化治疗方案,提高疾病诊治水平。
作者 郭志勇 谌卫
出处 《中国中西医结合肾病杂志》 2015年第11期941-942,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
基金 国家自然科学基金资助项目(No.81270773 81403261) 上海市科委中药支撑计划项目(No.13401900105) 上海市教委科研项目(No.14ZZ080) 第二军医大学长海医院学科提升项目(No.CH125520301)
  • 相关文献

参考文献15

  • 1Ziemba JB, Matlaga BR. Guideline of Guidelines : Kidney Stones. BJU Int,2015,16(2) :45 -49.
  • 2Ferraro PM, Robertson WG, Johri N, et al. A London experience 1995 - 2012 : demographic, dietary and biochemical characteris- tics of a large adult cohort of patients with renal stone disease. QJM ,2015,108 (7) :561 - 568.
  • 3El -Zoghby ZM, Lieske JC,Foley RN, et al. Urolithiasis and the risk of ESRD. Clin J Am Soc Nephrol, 2012,7 ( 9 ) : 1409 - 1415.
  • 4Liu Y, Li S, Zeng Z, et al. Kidney stones and cardiovascular risk: a meta - analysis of cohort studies. Am J Kidney Dis, 2014,64 (3) :402 -410.
  • 5陈希,谌卫,丁家荣,殷晶晶,胡海燕,贾猛,郭志勇.泌尿系结石患者血脂及相关影响因素的研究[J].中国全科医学,2011,14(34):3924-3926. 被引量:11
  • 6殷晶晶,谌卫,丁家荣,郭志勇,黄勤.糖尿病、高血压对肾结石患者首次发病年龄的影响[J].国际泌尿系统杂志,2012,32(6):763-767. 被引量:9
  • 7Khan SR. Is oxidative stress, a link between nephrolithiasis and obesity, hypertension, diabetes, chronic kidney disease, metabolic syndrome. Urol Res, 2012,40 ( 2 ) : 95 - 112.
  • 8张优,高小峰,彭永涵,谌卫,彭忠将,汪丽,郭志勇.单中心泌尿系统结石术后急性肾损伤的流行病学调查[J].上海医学,2014,37(5):386-388. 被引量:6
  • 9Peng Z, Chen W, Gao S, et al. Therapeutic effect of Xue Niao An on glyoxylate- induced calcium oxalate crystal deposition based on urinary metabonomics approach. J Clin Biochem Nutr,2014, 5"5(3): 184 -190.
  • 10Gao 5, Chen W, Peng Z, et al. Urinary metabonomies elucidate the therapeutic mechanism of Orthosiphon stamineus in mouse crystal - induced kidney injury. J Ethnopharmacol, 2015,166 : 323 - 332.

二级参考文献81

  • 1李大伟,林飞鹤.泌尿系结石396例临床分析[J].广东医学,2005,26(3):374-375. 被引量:10
  • 2刘岩峰,吴晓宇.泌尿系结石在中国的流行病学特点[J].中国社区医师(医学专业),2005,7(9):4-5. 被引量:42
  • 3Soucie JM,Coates RJ,McClellan W,et al.Relation between geographic variability in kidney stones prevalence and risk factors for stones[J].Am J Epidemiol,1996,143:487-495.
  • 4Cirillo M,Laurenzi M.Elevated blood pressure and positive history of kidney stones:results from a population-based study[J].J Hypertens,1988,6 (Suppl 4):484-486.
  • 5Sakhaee K,Adams-Huet B,Moe OW,et al.Pathophysiologic basis for normouricosuric uric acid nephrolithiasis[J].Kidney Int,2002,62:971-979.
  • 6Jeong IG,Kang T,Tang JK,et al.Association between metabolic syndrome and the presence of kidney stones in a screened population[J].Am J Kidney Dis,2011,58(3):383-388.
  • 7Atakan IH,Kaplan M,Seren G,et al.Serum,urinary and stone zinc,iron,magnesium and copper levels in idiopathic calcium oxalate stone patients[J].Int Urol Nephrol,2007,39(2):351-356.
  • 8Mufioz JA,Valiente M.Effects of trace metals on the inhibition of calcium oxalate crystallization[J].Urol Res,2005,33(4):267-272.
  • 9Park KJ,Jeon SS,Han DH,et al.Clinical and metabolic evaluation of Korean patients with urolithiasis[J].Scand J Clin Lab Invest,2011,71(6):481-485.
  • 10Taylor EN,Stampfer MJ,Curhan GC.Obesity,weight gain,and the risk of kidney stones[J].JAMA,2005,293:455-462.

共引文献36

同被引文献116

引证文献5

二级引证文献39

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部