关节腔灌洗联合医用三氧注射治疗膝骨性关节炎的疗效

Efficacy of articular cavity lavage combined with medical ozone injection in the treatment of patientswith knee osteoarthritis

目的观察关节腔灌洗联合医用三氧注射治疗膝关节骨性关节炎的临床疗效。方法膝骨性关节炎患者98例，其中灌洗组（A组）50例，患者均采用膝关节灌洗联合医用三氧注射治疗，每3日灌洗1次，3次为1疗程。医用三氧组（B组）48例，膝关节腔只注射医用三氧，每3日1次，3次为1疗程。观察治疗后1周及6个月时患者VAS值，并评估治疗效果。结果与治疗前比较，两组患者治疗后1周及6个月时VAS均下降；与B组比较，A组治疗后1周及6个月时VAS均较低，差异均有统计学意义（P〈0．05）。治疗后6个月时，A组优效率（94％，47／50例）与总有效率（98．0％，49／50例）高于B组的优效率（54％，26／48例）与总有效率（79．1％，38／48例），差异有统计学意义（P〈0．05）。结论膝关节腔灌洗联合医用三氧注射治疗膝骨性关节炎疗效确切、持久。

Objective To observe the clinical efficacy of articular cavity lavage and medical ozone injection in the treatment of knee osteoarthritis. Methods There were ninety-eight patients with knee osteoar- thritis, of whom 50 patients received knee-joint cavity lavage combined with medical ozone injection in the lavage group （group A）, 48 patients received medical ozone injection into the knee-joint cavity in the medical ozone group （group B）. All patients were treated every 3 days, 3 times for 1 course. VAS was recorded at 1 week, 6 months after the treatment and the efficacy of treatment was assessed. Results VAS was significantly decreased after the treatment in the two groups （P〈 0.05）. Compared with group B, VAS was significantly lower at 1 week and 6 months after the treatment in group A （P〈 0.05）. The excellent and total effective rates were higher in group A （94%, 47/50 cases and 98.0%, 49/50 cases） than those in group B （54%, 26/48 cases and 79.1%, 38/48 cases） at 6 months after the treatment （P 〈 0.05）. Conclusion Efficacy of articular cavity lavage combined with medical ozone injection is definite and long-term in the treatment of patients with knee osteoar- thritis.