摘要
目的:明确通督调神针刺法对VCIND患者认知功能的治疗效果,并观察通督调神针刺对患者P300潜伏期和波幅的影响。方法:63例VCIND患者随机分为针药组32例和西药组31例。西药组予口服奥拉西坦胶囊,针药组加用通督调神针刺治疗,观察两组患者治疗前和治疗8周后的MMSE、Mo CA积分及事件相关电位P300指标数值的变化。结果:治疗后针药组和西药组的P300潜伏期缩短,波幅增高,差值有统计学意义(P<0.05)。针药组和西药组治疗总有效率为93.75%、70.96%,组间有效率有显著差异性(P<0.05)。结论:通督调神针刺方法的配合使用增加了对VCIND患者认知功能的改善,疗效明显优于单纯西药组。ERP-P300可以较客观地显示出VCIND患者早期认知功能损害的程度,能及时有效地诊断患者的早期认知功能障碍,并评价其预后。
Objective:To detect whether Tongdu Tiaoshen acupuncture method is valid for enhancing cognitive function and quality of life for patients with VCIND,and observe the change of ERP-P300 latency and amplitude after Tongdu Tiaoshen acupuncture treatment. Methods:Sixtythere cases were randomly divided into 2 groups,with 32 in the acupuncture-medicine group and 31 in the medicine group. The medicine group used oral Oxiracetam Capsules and the acupuncturemedicine group added Tongdu Tiaoshen acupuncture for a course of 8 weeks. The changes of scores for MMSE and Mo CA were investigated,and P300 was checked before and after treatment in both groups. Results:The two groups manifested shorter latency and higher amplitude on P300 after treatment,and the differences were significant(P〈0.05).The total effective rates in the acupuncture-medicine group and medicine group were 93.75% and 70.96% respectively with a significant difference(P〈0.05),indicating that the curative effect of the acupuncture- medicine group was better than the medicine group. Conclusion:Increased use of Tongdu Tiaoshen acupuncture method can improve the cognitive function in patients with VCIND,and the curative effect is superior to the group with only medicine treatment.ERP-P300 check can objectively reflect the degree of early cognitive dysfunction on VCIND patients. It is beneficial for early diagnosis of cognitive dysfunction.
出处
《辽宁中医药大学学报》
CAS
2016年第1期149-151,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
安徽中医学院青年科研基金项目(2013qn037)