降钙素原及超敏C反应蛋白检测在新生儿脓毒血症诊断治疗中的意义

Significance of procalcitonin and high sensitivity C-reactive protein detection in diagnosis and treatment of neonatal sepsis

目的探讨降钙素原(PCT)以及超敏C反应蛋白(hs-CRP)检测在新生儿脓毒血症中的意义。方法 73例新生儿脓毒血症患儿作为观察组,同期73例非感染性患儿作为对照组,采集两组患儿的静脉血进行血常规、PCT以及hs-CRP检测,对比两组患儿的检测结果。结果对照组与观察组患儿血清PCT以及hs-CRP的检测结果比较,差异具有统计学意义(P<0.05),两组血常规结果检测比较,差异无统计学意义(P>0.05)。结论血清PCT以及hs-CRP在新生儿脓毒血症的诊断中具有重要意义,为疾病的早诊断早治疗奠定基础,值得在临床上推广与应用。

Objective To investigate significance of procalcitonin（PCT） and high sensitivity C-reactive protein（hs-CRP） detection in diagnosis and treatment of neonatal sepsis. Methods There were 73 newborn with neonatal sepsis as observation group, and another 73 non-infective newborn as control group. Venous bloods were taken from both groups for detection of blood routine, PCT and hs-CRP. Detection results of the two groups were compared. Results The difference of PCT and hs-CRP detection in the two groups had statistical significance（P0.05）. The difference of blood routine had no statistical significance（P〉0.05）. Conclusion PCT and hs-CRP contain important significance in diagnosis of neonatal sepsis. They can lay a foundation for early diagnosis and treatment. It is worthy of clinical promotion and application.