绿茶和2型糖尿病关系的现况研究

Association between green tea and the prevalence of type 2 diabetes mellitus in population of Xuzhou city

目的探讨饮用绿茶和2型糖尿病（T2DM）的关系。方法采用多阶段整群随机抽样，抽取徐州市25岁及以上常住居民26828人。通过横断面调查，采用自行设计的调查问卷收集研究对象一般人口学特征，疾病史和家族史，饮食、生活行为方式和饮茶史，并进行体格检查；利用χ^2检验或Z检验进行组间比较，通过多因素logistic回归进行统计学分析。结果徐州市居民T2DM患病率为6．50％，饮用绿茶率为18．27％；调整了年龄、性别、家族史、慢性病史及体质指数等多因素后，饮用绿茶对2型糖尿病的OR（95％CI）为0．62（0．51，0．89）；其中，男性饮用绿茶对2型糖尿病的OR（95％CI）为0．61（0．43～0．87），女性饮用绿茶对2型糖尿病的0R（95％CI）为0．64（0．53—0．91）。随着饮用频次和杯数的增加，患T2DM的风险性降低。结论饮用绿茶和T2DM之间呈现负性关联，能够降低T2DM的患病风险，饮茶的频次与T2DM的患病之间存在着剂量反应关系。

Objective To explore the association between green tea consumption and risk of type 2 diabetes. Methods A multistage cluster, random-sampling method was used to select a representative sample from Xuzhou. In total, 26 828 urban inhabitants aged 25 years or older were enrolled in this study. A standard questionnaire was used to collect data on general demographic characteristics, diseases history and family history, dietary factor, life behavior, green tea consumption history and other confounding factors. Comparisons between groups were carried out with χ^2 test or Z test for qualitative data and quantitative data respectively. Logistic regression was used for the analysis of relation between green tea and T2DM. Results The prevalence rate of type 2 diabetes and the rate of green tea consumption among urban inhabitants in Xuzhou areas was 6.50% and 18.27% respectively. After adjusting for age, gender, family disease history, body mass index, etc, the OR （95%CI） was 0.62 （0.51-0.89）. The OR （95%CI） in men and women respectively were 0.61 （0.43-0.87） and 0.64（0.53-0.91）. Subjects who consumed the more green tea showed lower risk of T2DM. Conclusion Consumption of green tea may protect against the development of T2DM in Xuzhou. There was a dose-response relationship between frequency and dosage of green tea consumption and the risk of T2DM.