580例自发性脑出血患者综合治疗加高压氧治疗疗效分析

Efficacy analysis of comprehensive treatment and hyperbaric oxygen therapy in 580 cases of spontaneous intracerebral hemorrhage

目的:评价综合治疗加高压氧治疗对自发性脑出血患者的临床疗效。方法:将2011年1月至2014年10月收治的580例自发性脑出血患者作为研究组,同时将2006年1月至2010年12月收治的另490例患者作为对照组。对照组实行开颅去骨瓣减压、钻孔引流、脑室引流等手术及对症、支持等综合治疗措施;研究组在对照组的基础上给予高压氧进行治疗。对比两组临床疗效、死亡率及治疗前后肢体运动功能、日常生活活动能力。结果:研究组治疗的总有效率为88.97%,高于对照组的83.88%(P<0.05);研究组死亡率为2.07%,低于对照组的4.69%(P<0.05);研究组治疗前肢体运动功能得分(21.26±11.82)分,与对照组的(21.93±12.69)分无明显差异(P>0.05);研究组治疗后肢体运动功能得分(65.63±12.15)分,高于对照组的(53.82±12.28)分(P<0.05);研究组治疗前日常生活活动能力得分为(29.83±13.38)分,与对照组的(29.15±13.62)分差异无统计学意义(P>0.05);研究组治疗后日常生活活动能力得分为(70.42±13.92)分,高于对照组的(57.21±14.37)分(P<0.05)。结论:在综合治疗的基础上采用高压氧对自发性脑出血患者进行治疗可有效的提高治疗效果,降低死亡率,并改善预后。

Objective： To evaluate combined therapy plus hyperbaric oxygen therapy clinical efficacy of spontaneous intracerebral hemorrhage patients. Methods： From January 2011 to 2014 October 580 cases of spontaneous intracerebral hemorrhage as the study group,while the other 490 cases of patients from January 2006 to December 2010 were treated as the control group. Group practice craniotomy decompressive craniectomy,drilling drainage,and other surgical ventricular drainage and symptomatic and supportive measures,such as comprehensive treatment; study group received hyperbaric oxygen therapy on the basis of the control group. Compare clinical efficacy,and mortality before and after treatment motor function,activities of daily living. Results： Research group therapy effective rate was 88. 97%,which was higher than 83. 88% of control group（ P〈0. 05）; study group mortality rate was 2. 07%,down from4. 69% in the control group（ P〈0. 05）; limb motor function score points has no significant difference（ 21. 26 ± 11. 82 vs 21. 93 ±12. 69,P〉0. 05） before treatment between the study groupand the control group; limb motor function score points in the study group was higher than that in the control group（ after treatment（ 65. 63 ± 12. 15 vs 53. 82 ± 2. 28,P〈0. 05）; the study group before treatment,activities of daily living score was no significant difference（ 29. 83 ± 13. 38 vs 29. 15 ± 13. 62,P〉0. 05））; study group therapy after the ADL score was higher than that of control group（ 70. 42 ± 13. 92 vs 57. 21 ± 14. 37,P〈0. 05））. Conclusion： The comprehensive use and hyperbaric oxygen therapy on patients with spontaneous intracerebral hemorrhage treatment can effectively improve the therapeutic effect,reduce mortality and improve prognosis.