血栓通对地震多发性肋骨骨折患者的临床回顾性研究

Efficacy of Xueshuantong injection for pulmonary contusion caused by earthquake

目的:研究血栓通对地震多发性肋骨骨折患者的治疗作用。方法:采用回顾性研究方法,收集"5·12"地震多发性肋骨骨折患者35例,常规西医加血栓通注射液治疗组18例,常规西医治疗组17例,对比两组干预治疗前、干预治疗后1周、2周疼痛程度变化、镇痛药使用时间、动脉血氧饱和度和平均住院时间。结果:西医加血栓通治疗组在改善患者疼痛(P=0.029、P=0.000)、呼吸机使用时间(P=0.029、P=0.000)镇痛药使用时间(P=0.026、P=0.000、P=0.000)、血氧饱和度(P=0.045、P=0.029)缩短住院时间(P=0.021、P=0.037、P=0.028)与西医治疗组比较均有统计学差异。结论:西医加血栓通治疗方案促进了多发性肋骨骨折患者的症状改善,缩短患者的平均住院时间和减少镇痛药物的使用。

Objective：To analyze the efficacy of combination of western medicine plus Xueshuantong injection in the treatment of pulmonary contusion caused by Wenchuan earthquake. Methods：Totally 35 pulmonary contusion patients were enrolled and simple treatment of western medicine（n=17） and western medicine plus Xueshuantong injection（n=lS） were conducted, respectively. Oxygen saturation in arterial blood and the change of thoracic X-Ray were measured at baseline, one week and two weeks. The use of mechanical ventilation and durations of mechanical ventilation and hospital stay were also recorded. Results ： Compared with simple treatment of western medicine group, the western medicine plus Xueshuantong injection group was superior in the change of thoracic X-Ray（P=0.034,P=0.15）,durations of mechanical ventilation（P=0.020,P=0.046） and hospital stay（P=0.021,P=0.037,P=0.028）. Conclusion ：Western medicine plus Xueshuantong injection shortens the durations of hospital stay,reduces the use of mechanical ventilation, and is conducive to the recovery of pulmonary contusion.