摘要
Widely used in clinical research, the database is a new type of data management automation technology and the most efficient tool for data management. In this article, we first explain some basic concepts, such as the definition, classification, and establishment of databases. Afterward, the workflow for establishing databases, inputting data, verifying data, and managing databases is presented. Meanwhile, by discussing the application of databases in clinical research, we illuminate the important role of databases in clinical research practice. Lastly, we introduce the reanalysis of randomized controlled trials(RCTs) and cloud computing techniques, showing the most recent advancements of databases in clinical research.
Widely used in clinical research, the database is a new type of data management automation technology and the most efficient tool for data management. In this article, we first explain some basic concepts, such as the definition, classification, and establishment of databases. Afterward, the workflow for establishing databases, inputting data, verifying data, and managing databases is presented. Meanwhile, by discussing the application of databases in clinical research, we illuminate the important role of databases in clinical research practice. Lastly, we introduce the reanalysis of randomized controlled trials（RCTs） and cloud computing techniques, showing the most recent advancements of databases in clinical research.
基金
supported by Fundamental Research Funds of State Key Laboratory of Ophthalmology (Grant No.2015QN01)
Young Teacher Top-Support project of Sun Yat-sen University(Grant No.2015ykzd11)
the Cultivation Projects for Young Teaching Staff of Sun Yat-sen University(Grant No.12ykpy61) from the Fundamental Research Funds for the Central Universities
the Pearl River Science and Technology New Star(Grant No.2014J2200060)
Project of Guangzhou City,the Guangdong Provincial Natural Science Foundation for Distinguished Young Scholars of China(Grant No. 2014A030306030)
Youth Science and Technology Innovation Talents Funds in Special Support Plan for High Level Talents in Guangdong Province(Grant No. 2014TQ01R573)
Key Research Plan for National Natural Science Foundation of China in Cultivation Project (No.91546101)
