88例阻塞性睡眠呼吸暂停综合症血液检测分析

Analysis of testing of obstructive sleep apnea syndrome patients' blood 88 cases

目的通过对阻塞性睡眠呼吸暂停综合症(OSAS)血液检测分析,探寻OSAS患者早期诊断和预防的参考依据。方法选取88例确认OSAS患者,进行RBC、Hb、HCT、血脂测定[甘油三脂(TG)、低密度脂蛋白(LDLC)、高密度脂蛋白(HDL-C)、总胆固醇(TC)]、尿酸(UA)等检测,检测结果与80例健康体检者进行比较。结果OSAS组与对照组RBC、HCT测定结果升高,结果对比具有统计学意义(P<0.05)。OSAS组TC、TG、LDLC、UA测定结果升高,其中TG、LDL-C项目测定结果与对照组比较具有显著性差异(P<0.01),TC、UA项目测定结果与对照组比较差异具有统计学意义(P<0.05)。OSAS组HDL-C测定结果较对照组降低,两组比较差异具有统计学意义(P<0.05)。结论 OSAS患者存在红细胞参数异常、血脂和尿酸代谢异常,积极正确地诊断和治疗OSAS可有效减少心血管疾病的发生。

Objective Through the testing of obstructive sleep apnea syndrome（ OSAS） patients＇ blood,we＇d like to find out the methods that could interfere the OSAS at the early stage and the prevention of the OSAS. Methods Our study included 88 patients who were recently diagnosed with OSAS and never received therapy. The control group consisted of 80 healthy persons in whom OSAS was excluded. Eighty- eight OSAS patients＇ blood and eighty healthy persons＇ blood were separately tested of RBC,Hb,HCT,blood lipids（ including TG,LDL- C,HDL- C,TC） and UA,then the results were compared with each other. Results There is a significant differences（ P〈0. 05） between the OSAS patients and the controls in the testing of RBC and HCT. The content of TC,TG,LDL- C,UA in the OSAS group＇blood were higher those than the controls,especially the TG and LDL- C were significantly higher（ P〈0. 01）,while the increase of TC and UA was statistically significant（ P〈0. 05）. In comparison to the controls,the content of HDL- C in tzhengquezzhenghe OSAS group blood was significantly decreased（ P〈0. 05）. Conclusion The results suggest OSAS patients usually have the high risk of blood lipids and UA metabolic disorders,and they are also easily to get a abnormal amount of RBC. Diagnosing and treatment of the OSAS patients correctly should have very positive results in the cardiovascular disease decreases.