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肿瘤相关性骨软化症一例并文献复习 被引量：1

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摘要 肿瘤相关性低血磷性骨软化症（tumor-induced osteomalacia,TIO）是以低血磷、高尿磷及1,25-二羟维生素D正常或低下为特点的一种少见疾病。典型的是由生长缓慢的间叶组织或混合性结缔组织肿瘤导致的临床综合征,其起病隐匿、发展缓慢,临床上常误诊及漏诊[1]。本文就重庆医科大学附属第一医院内分泌内科收治的1例TIO患者报道并复习相关文献。
作者 潘婷婷 王小菊 冯正平 周波
机构地区 重庆医科大学附属第一医院内分泌内科
出处 《中华关节外科杂志（电子版）》 CAS 2015年第6期94-95,共2页 Chinese Journal of Joint Surgery(Electronic Edition)
关键词 肿瘤相关性 骨软化症 结缔组织肿瘤 血磷 间叶组织 临床综合征 混合性 骨密度 骨小梁稀疏 甲状旁腺素
分类号 R681 [医药卫生—骨科学] R730.5 [医药卫生—肿瘤]
  • 相关文献

参考文献8

  • 1Amblee A, Uy J, Senseng C, et al. Tumor-induced osteomalacia with normal systemic fibroblast growth factor-23 level [ J ]. ClinKidney J, 2014, 7:186 - 189.
  • 2Jan de Beur SM, Levine MA. Molecular pathogenesis of hypophosphatemic rickets[J]. J Clin Endocrinol Metab, 2002, 87: 2467 - 2473.
  • 3吴丹,巴建明,谷伟军,金楠,杨国庆,母义明,窦京涛,吕朝晖.阿德福韦酯致肾小管酸中毒并低磷骨软化症3例临床分析[J].中国骨质疏松杂志,2012,18(11):1058-1061. 被引量：10
  • 4Quarles LD. FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization [ J ]. Am J Physiol Endoerinol Metab, 2003, 285 : E1 - E9.
  • 5Folpe AL, Fanburg-Smith JC, Billings SD, et al. Most osteomalaeia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literature[J]. Am J Surg Pathol, 2004, 28:1 -30.
  • 6Jiang Y, Xia WB, Xing XP, et al. Tmnor-induced osteomalacia: an impmlant cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature[J]. J Bone Miner Res, 2012, 27 : 1967 - 1975.
  • 7Shimada T, Mizutarti S, Muto T, et al. Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia[J]. Proc Natl Acad Sci U S A, 2001, 98:6500-6505.
  • 8Tajima S, Fukayama M. CD56 Mar' be a more useful immunohistochemical marker than somatostatin receptor 2A for the diagnosis of phosphaturic mesenehymal tumors[J]. Int J Clin Exp Pathol, 2015, 8:8159-8164.

二级参考文献11

  • 1Fontana RJ. Side effects of long-term oral antiviral therapy for hepatitis B[J].Hepatology,2009,(5 Supp1):S185-S195.
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中华关节外科杂志（电子版）
2015年 第6期

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